Evidence map›Paper›PMID 38272796›Full record

ArticleInternational wound journal2024

Evaluating the efficacy of recombinant human growth factors in scar remodelling for patients with facial soft tissue injuries.

Baiyu Zhang, Zonghai He, Hui Zhao, Hongbin Gao, Zhiying Zhang, Zhenhua Gao, Kunbin Ke

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in International wound journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Baiyu ZhangThe First Department of Urology, The First Affiliated Hospital of Kunming Medical University, Kunming, China.
Zonghai HeThe First Department of Urology, The First Affiliated Hospital of Kunming Medical University, Kunming, China.
Hui ZhaoThe First Department of Urology, The First Affiliated Hospital of Kunming Medical University, Kunming, China.
Hongbin GaoThe First Department of Urology, The First Affiliated Hospital of Kunming Medical University, Kunming, China.
Zhiying ZhangThe First Department of Urology, The First Affiliated Hospital of Kunming Medical University, Kunming, China.
Zhenhua GaoThe First Department of Urology, The First Affiliated Hospital of Kunming Medical University, Kunming, China.ORCID https://orcid.org/0000-0002-5806-2891
Kunbin KeThe First Department of Urology, The First Affiliated Hospital of Kunming Medical University, Kunming, China.
Kunming Medical University · CN

Funding

Sub-project of Yunnan Province Clinical Research Center for Chronic Kidney Disease 202102AA100060Ten Thousand Talent Plans for Young Top-notch Talents of Yunnan Province RLQB20200005The National Natural Science Foundation of China 81960133The National Natural Science Foundation of China 82360294
6 · The paper itself

Abstract

Facial soft tissue injuries, often resulting in scarring, pose a challenge in reconstructive and aesthetic surgery due to the need for functional and aesthetic restoration. This study evaluates the efficacy of recombinant human growth factors (rhGFs) in scar remodelling for such injuries. A retrospective evaluation was conducted from January 2020 to January 2023, involving 100 patients with facial soft tissue injuries. Participants were divided equally into a control group, receiving standard cosmetic surgical repair, and an observation group, treated with rhGFs supplemented cosmetic surgery. The study assessed scar characteristics (pigmentation, pliability, vascularity, height), hospital stay duration, tissue healing time, complication rates and patient satisfaction. The observation group demonstrated significant improvements in all scar characteristics, with notably better pigmentation, pliability, vascularity and height compared with the control group. The rhGF treatment also resulted in reduced hospital stay duration and faster tissue healing. Notably, the total complication rate was significantly lower in the observation group (10%) compared with the control group (34%). Additionally, patient satisfaction levels were higher in the observation group, with 98% combined satisfaction compared with 76% in the control group. The application of rhGFs in treating facial soft tissue injuries significantly enhances scar remodelling, expedites healing, reduces complications and improves patient satisfaction. These findings establish rhGFs as a valuable tool in the management of facial soft tissue injuries, highlighting their potential in improving both functional and aesthetic outcomes.

Indexed as

Facial InjuriesPlastic Surgery ProceduresSoft Tissue InjuriesCicatrixHumansRetrospective StudiesTreatment OutcomeWound Healingfacial soft tissue injuriesrecombinant human growth factorsscar remodellingwound healing

Identifiers

PMID38272796
PMCPMC10789918
OpenAlexW4390919490

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.