ArticleEnvironmental research2024
Prenatal current-use pesticide exposure and children's neurodevelopment at one year of age in the Infants' Environmental Health (ISA) birth cohort, Costa Rica.
Article in Environmental research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 19 citations in OpenAlex.
- Article
- The Impact of Endocrine Disruptor Exposure During Pregnancy on Bacterial Complications and Viral Infections: A Narrative Review.Microorganisms · 2026Review
- Pesticide Contamination in the Hair of Children From Colonia San Juan, a Rural Community in Paraguay.Drug testing and analysis · 2026Article
- Evaluation of Passive Air Sampling for Monitoring Current-Use Pesticide Pollution near Large-Scale Banana Plantations in Costa Rica.Environmental science & technology · 2026Article
- NEURODEVELOPMENTAL DISRUPTION INDUCED BY LONG-TERM LOW-DOSE HERBICIDE EXPOSURE: BEHAVIORAL AND NEUROPATHOLOGICAL EVIDENCE FROM A RAT MODEL.Farmacia (Bucharest, Romania) · 2026Article
- Associations between concurrent neonicotinoid, pyrethroid, and organophosphate insecticide metabolites and neurocognitive performance in Ecuadorian adolescents.The Science of the total environment · 2025Article
- Endocrine Disrupting Agents: Toxicological Aspects on Male Reproduction.Reproductive sciences (Thousand Oaks, Calif.) · 2025Review
- QTAIM Based Computational Assessment of Cleavage Prone Bonds in Highly Hazardous Pesticides.Toxics · 2025Article
- Children's environmental and occupational exposures to pesticides in low- and middle-income countries rural areas - an elephant in the room.The Science of the total environment · 2025Article
- Development and child health in a world of synthetic chemicals.Pediatric research · 2025Review
- Article
- Article
- Pesticide Exposures during Pregnancy and Health Outcomes in Latin America and the Caribbean: A Scoping Review of Human Observational Studies.Journal of health & pollution · 2024Review
- Herbicide Mixture-Driven Neurotoxicity in the Maternal Brain: Combined Exposure Produces Greater-Than-Individual Effects at Regulatory Relevant Doses.Current health sciences journalArticle
Corrections and comments
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Authors and funding
8 authors at 6 institutions in 5 countries.
Funding
Abstract
backgroundPesticide exposure may affect young children's neurodevelopment, but only few cohort studies have addressed possible effects of non-organophosphate pesticides.
objectiveWe evaluated associations between prenatal current-use pesticide exposure and neurodevelopmental outcomes among 1-year-old children from the Infants' Environmental Health (ISA) birth cohort.
methodsTo determine prenatal pesticide exposure, we measured biomarkers of pyrimethanil, chlorpyrifos, synthetic pyrethroids, and 2,4-D in urine samples among 355 women, 1-3 times during pregnancy. One-year post-partum, we evaluated children's neurodevelopment with the Bayley Scales of Infant and Toddler Development 3rd edition (BSID-III). We assessed associations between exposures and neurodevelopmental outcomes (composite and z-scores) using single-chemical linear regression models adjusted for possible confounders (maternal education, parity, sex, gestational age at birth, child age, HOME-score, location of assessment, biomarkers of mancozeb), and studied effect-modification by sex. We evaluated non-linear associations of multiple pesticide exposures with Bayesian kernel machine regression (BKMR).
resultsWe found higher prenatal urinary 2,4-D concentrations were associated with lower language (β DISCUSSION: Prenatal exposure to common-use pesticides may affect children's neurodevelopment at 1-year of age, some effects may be sex-specific.
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