Evidence map›Paper›PMID 38272004›Full record

ArticleRespiration; international review of thoracic diseases2024

Photon Counting Computed Tomography with the Radiation Dose of a Chest X-Ray: Feasibility and Diagnostic Yield.

Sabine Dettmer, Thomas Werncke, Violeta Nikolova Mitkovska, Torben Brod, Oana Joean, Jens Vogel-Claussen, Frank Wacker, Tobias Welte, Jessica Rademacher

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Respiration; international review of thoracic diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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  7. Imaging the Lung in ARDS: A Primer.Respiratory care · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Sabine DettmerInstitute of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.
Thomas WernckeInstitute of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.
Violeta Nikolova MitkovskaInstitute of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.
Torben BrodEmergency Department, Hannover Medical School, Hannover, Germany.
Oana JoeanDepartment of Respiratory Medicine and Infectious Diseases, Hannover Medical School, Hannover, Germany.
Jens Vogel-ClaussenInstitute of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.
Frank WackerInstitute of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.
Tobias WelteBiomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Member of the German Center for Lung Research (DZL), Hannover, Germany.
Jessica RademacherBiomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Member of the German Center for Lung Research (DZL), Hannover, Germany.
Medizinische Hochschule Hannover · DEGerman Center for Lung Research · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPhoton counting (PC) detectors allow a reduction of the radiation dose in CT. Chest X-ray (CXR) is known to have a low sensitivity and specificity for detection of pneumonic infiltrates. The aims were to establish an ultra-low-dose CT (ULD-CT) protocol at a PC-CT with the radiation dose comparable to the dose of a CXR and to evaluate its clinical yield in patients with suspicion of pneumonia.

methodsA ULD-CT protocol was established with the aim to meet the radiation dose of a CXR. In this retrospective study, all adult patients who received a ULD-CT of the chest with suspected pneumonia were included. Radiation exposure of ULD-CT and CXR was calculated. The clinical significance (new diagnosis, change of therapy, additional findings) and limitations were evaluated by a radiologist and a pulmonologist considering previous CXR and clinical data.

resultsTwenty-seven patients (70% male, mean age 68 years) were included. With our ULD-CT protocol, the radiation dose of a CXR could be reached (mean radiation exposure 0.11 mSv). With ULD-CT, the diagnosis changed in 11 patients (41%), there were relevant additional findings in 4 patients (15%), an infiltrate (particularly fungal infiltrate under immunosuppression) could be ruled out with certainty in 10 patients (37%), and the therapy changed in 10 patients (37%). Two patients required an additional CT with contrast medium to rule out a pulmonary embolism or pleural empyema.

conclusionsWith ULD-CT, the radiation dose of a CXR could be reached while the clinical impact is higher with change in diagnosis in 41%.

Indexed as

PneumoniaTomography, X-Ray ComputedAdultAgedFeasibility StudiesFemaleHumansMaleRadiation DosageRetrospective StudiesX-RaysCommunity-acquired pneumoniaPhoton counting computed tomographyUltra-low-dose computed tomography

Identifiers

PMID38272004
PMCPMC10871675
OpenAlexW4391213588

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.