Evidence map›Paper›PMID 38271683›Full record

ArticleAmerican journal of respiratory cell and molecular biology2024

FTO Deficiency Alleviates LPS-induced Acute Lung Injury by TXNIP/NLRP3-mediated Alveolar Epithelial Cell Pyroptosis.

Wei-Ming Xie, Wei Su, Xin-Yu Liu, Junhao Zhou, Min Wang, Yuchang Wang, Wei Wang, Xiangjun Bai, Zhanfei Li, Tianyu Li

Abstract read
PubMed Publisher
In one paragraph

Article in American journal of respiratory cell and molecular biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Acute lung injury: pathogenesis and treatment.Journal of translational medicine · 2025
    Review
  10. Article
  11. Mitigation of nicotine-induced podocyte injury through inhibition of thioredoxin interacting protein.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2025
    Article
  12. Brazilin alleviates acute lung injury via inhibition of ferroptosis through the SIRT3/GPX4 pathway.Apoptosis : an international journal on programmed cell death · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Tamping Down the Fire: Taming Pyroptosis through RNA Methylation in Acute Lung Injury.American journal of respiratory cell and molecular biology · 2024
    Article
  18. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Wei-Ming XieDivision of Trauma Surgery, Emergency Surgery & Surgical Critical, Tongji Trauma Center, and.
Wei SuDivision of Trauma Surgery, Emergency Surgery & Surgical Critical, Tongji Trauma Center, and.
Xin-Yu LiuDivision of Trauma Surgery, Emergency Surgery & Surgical Critical, Tongji Trauma Center, and.
Junhao ZhouSchool of Laboratory Medicine, Hubei University of Chinese Medicine, Wuhan, China.
Min WangDepartment of Emergency and Critical Care Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; and.
Yuchang WangDivision of Trauma Surgery, Emergency Surgery & Surgical Critical, Tongji Trauma Center, and.
Wei WangDivision of Trauma Surgery, Emergency Surgery & Surgical Critical, Tongji Trauma Center, and.
Xiangjun BaiDivision of Trauma Surgery, Emergency Surgery & Surgical Critical, Tongji Trauma Center, and.
Zhanfei LiDivision of Trauma Surgery, Emergency Surgery & Surgical Critical, Tongji Trauma Center, and.
Tianyu LiDivision of Trauma Surgery, Emergency Surgery & Surgical Critical, Tongji Trauma Center, and.
Tongji Hospital · CNHuazhong University of Science and Technology · CNHubei University of Chinese Medicine · CN

Funding

Hubei Association of Pathophysiology 2021HBAP002National Natural Science Foundation of China 82000088Natural Science Foundation of Hubei Province 2021CFB026
6 · The paper itself

Abstract

N6-methyladenosine (m

Indexed as

Acute Lung InjuryAlpha-Ketoglutarate-Dependent Dioxygenase FTOAlveolar Epithelial CellsCarrier ProteinsLipopolysaccharidesMice, KnockoutNLR Family, Pyrin Domain-Containing 3 ProteinPyroptosisA549 CellsAdenosineAnimalsHumansMaleMiceMice, Inbred C57BLSignal TransductionAdenosineAlpha-Ketoglutarate-Dependent Dioxygenase FTOCarrier ProteinsFTO protein, humanFTO protein, mouseLipopolysaccharidesNLR Family, Pyrin Domain-Containing 3 ProteinNlrp3 protein, mouseN-methyladenosineThioredoxinsTXNIP protein, humanTxnip protein, mouseALIFTON6-methyladenosinepyroptosisTXNIP

Identifiers

PMID38271683
OpenAlexW4391213963

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.