Evidence map›Paper›PMID 38271647›Full record

ArticleJCO global oncology2024

Fecal Immunochemical Testing and the Risk of Advanced Colorectal Neoplasia: A Difference-In-Difference Analysis.

Guanglu Zhang, Yiying Wang, Lizhong Zhao, Mingqing Zhang, Weihua Zhang, Weituo Zhang, Shiwu Zhang, Huan Zhang, Dezheng Wang, Yijia Wang and 3 more

Abstract read
In one paragraph

Article in JCO global oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Temporal trends in colorectal resections for benign colorectal neoplasia: A retrospective cohort study of the ACS-NSQIP 2016-2022.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Guanglu ZhangHongqiao International Institute of Medicine, Shanghai Tongren Hospital and School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID 0000-0001-6600-8484
Yiying WangDepartment of Preventive and Health Care, Tianjin Union Medical Center, Nankai University, Tianjin, China.
Lizhong ZhaoDepartment of Colorectal Surgery, Tianjin Union Medical Center, Nankai University, Tianjin, China.
Mingqing ZhangDepartment of Colorectal Surgery, Tianjin Union Medical Center, Nankai University, Tianjin, China.
Weihua ZhangDepartment of Colorectal Surgery, Tianjin Hospital, Tianjin, China.
Weituo ZhangHongqiao International Institute of Medicine, Shanghai Tongren Hospital and School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID 0000-0002-4332-6663
Shiwu ZhangDepartment of Pathology, Tianjin Union Medical Center, Nankai University, Tianjin, China.ORCID 0000-0002-5052-2283
Huan ZhangCancer Prevention Center, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China.
Dezheng WangNCDs Preventive Department, Tianjin Centers for Disease Control and Prevention, Tianjin, China.
Yijia WangLaboratory of Oncologic Molecular Medicine, Tianjin Union Medical Center, Nankai University, Tianjin, China.
Li XieHongqiao International Institute of Medicine, Shanghai Tongren Hospital and School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID 0000-0003-1892-2217
Biyun QianHongqiao International Institute of Medicine, Shanghai Tongren Hospital and School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID 0000-0003-4587-7300
Xipeng ZhangDepartment of Colorectal Surgery, Tianjin Union Medical Center, Nankai University, Tianjin, China.ORCID 0009-0007-6259-1589

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the effectiveness of fecal immunochemical testing (FIT) in colorectal cancer screening.

methodsWe conducted a prospective cohort study among 5,598 participants age 40-74 years between 2012 and 2020 in Tianjin, China. Inverse probability weighting was adopted to adjust for potential imbalanced factors between groups. A Cox proportional hazards model was used to estimate the weighted associations between FIT screening and advanced colorectal neoplasia. A difference-in-difference (DID) model was adopted to compare the incidence rates of advanced colorectal neoplasia between groups.

resultsIn DID analysis, the rate of incidence was reduced by 0.34 cases per person-years in the screening group as compared with the historical FIT screening group (rate ratio [RR], 0.08 [95% CI, 0.07 to 0.10]) and by 0.06 cases per person-years in the non-FIT screening group as compared with the historical non-FIT screening group (RR, 0.37 [95% CI, 0.29 to 0.48];

conclusionFIT screening was associated with a reduction in incidence density from advanced colorectal neoplasia.

Indexed as

ColonoscopyColorectal NeoplasmsAdultAgedChinaHumansMiddle AgedOccult BloodProspective Studies

Identifiers

PMID38271647
PMCPMC10830093

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.