Evidence map›Paper›PMID 38271292›Full record

ArticlePLoS pathogens2024

The role of α-synuclein prion strains in Parkinson's disease and multiple system atrophy.

Chase R Khedmatgozar, Sara A M Holec, Amanda L Woerman

Open access · goldAbstract read
In one paragraph

Article in PLoS pathogens, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. The α-Synuclein Seeding Amplification Assay for Parkinson's Disease.International journal of molecular sciences · 2025
    Review
  5. Review
  6. Liquid-liquid phase separation and conformational strains ofFrontiers in molecular neuroscience · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Chase R KhedmatgozarDepartment of Microbiology, Immunology, and Pathology, Prion Research Center, Colorado State University, Fort Collins, Colorado, United States of America.
Sara A M HolecDepartment of Microbiology, Immunology, and Pathology, Prion Research Center, Colorado State University, Fort Collins, Colorado, United States of America.
Amanda L WoermanDepartment of Microbiology, Immunology, and Pathology, Prion Research Center, Colorado State University, Fort Collins, Colorado, United States of America.ORCID 0000-0003-4029-1968
Colorado State University · US

Funding

Effect of Agent and Host Factors on Alpha-Synuclein Strain PathogenesisR01NS121294 · NINDS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI Amanda L. Woerman · 2022 to 2026
$2.9M
A Novel Gene Therapy Approach to Prevent Alpha-synuclein Misfolding in Multiple System AtrophyR21NS127002 · NINDS · COLORADO STATE UNIVERSITY · PI WOERMAN, AMANDA L. · 2023 to 2024
$422k
NINDS NIH HHS R01 NS121294NINDS NIH HHS R21 NS127002
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Multiple System AtrophyParkinson DiseasePrionsalpha-SynucleinHumansalpha-SynucleinPrions

Identifiers

PMID38271292
PMCPMC10810466
OpenAlexW4391232096

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.