Evidence map›Paper›PMID 38270827›Full record

ArticleAnnals of surgical oncology2024

Multimodality Management of Thoracic Tumors: Initial Experience With a Multidisciplinary Thoracic Ablation Conference.

Alexander Graur, Jonathan A Saenger, Nathaniel D Mercaldo, Judit Simon, Eric D Abston, Melissa C Price, Kori Lanciotti, Lauren A Swisher, Yolonda L Colson, Henning Willers and 2 more

Abstract read
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In one paragraph

Article in Annals of surgical oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Alexander GraurDepartment of Radiology, Division of Thoracic Imaging and Intervention, Massachusetts General Hospital, Boston, MA, USA.
Jonathan A SaengerDepartment of Radiology, Division of Thoracic Imaging and Intervention, Massachusetts General Hospital, Boston, MA, USA.
Nathaniel D MercaldoDepartment of Radiology, Massachusetts General Hospital, Boston, MA, USA.
Judit SimonDepartment of Radiology, Division of Thoracic Imaging and Intervention, Massachusetts General Hospital, Boston, MA, USA.
Eric D AbstonDepartment of Surgery, Division of Thoracic Surgery, Massachusetts General Hospital, Boston, MA, USA.
Melissa C PriceDepartment of Radiology, Division of Thoracic Imaging and Intervention, Massachusetts General Hospital, Boston, MA, USA.
Kori LanciottiDepartment of Surgery, Division of Thoracic Surgery, Massachusetts General Hospital, Boston, MA, USA.
Lauren A SwisherDepartment of Surgery, Division of Thoracic Surgery, Massachusetts General Hospital, Boston, MA, USA.
Yolonda L ColsonDepartment of Surgery, Division of Thoracic Surgery, Massachusetts General Hospital, Boston, MA, USA.
Henning WillersDepartment of Radiation Oncology, Massachusetts General Hospital, Boston, MA, USA.
Michael LanutiDepartment of Surgery, Division of Thoracic Surgery, Massachusetts General Hospital, Boston, MA, USA.
Florian J FintelmannDepartment of Radiology, Division of Thoracic Imaging and Intervention, Massachusetts General Hospital, Boston, MA, USA. fintelmann@mgh.harvard.edu.ORCID http://orcid.org/0000-0002-0119-3903

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed to describe lesion-specific management of thoracic tumors referred for consideration of image-guided thermal ablation (IGTA) at a newly established multidisciplinary ablation conference.

methodsThis retrospective single-center cohort study included consecutive patients with non-small cell lung cancer (NSCLC) or thoracic metastases evaluated from June 2020 to January 2022 in a multidisciplinary conference. Outcomes included the management recommendation, treatments received (IGTA, surgical resection, stereotactic body radiation therapy [SBRT], multimodality management), and number of tumors treated per patient. Pearson's chi-square test was used to assess for a change in management, and Poisson regression was used to compare the number of tumors by treatment received.

resultsThe study included 172 patients (58 % female; median age, 69 years; 56 % thoracic metastases; 27 % multifocal primary lung cancer; 59 % ECOG 0 [range, 0-3]) assessed in 206 evaluations. For the patients with NSCLC, IGTA was considered the most appropriate local therapy in 12 %, equal to SBRT in 22 %, and equal to lung resection in 3 % of evaluations. For the patients with thoracic metastases, IGTA was considered the most appropriate local therapy in 22 %, equal to SBRT in 12 %, and equal to lung resection in 3 % of evaluations. Although all patients were referred for consideration of IGTA, less than one third of patients with NSCLC or thoracic metastases underwent IGTA (p < 0.001). Multimodality management allowed for treatment of more tumors per patient than single-modality management (p < 0.01).

conclusionsMultidisciplinary evaluation of patients with thoracic tumors referred for consideration of IGTA significantly changed patient management and facilitated lesion-specific multimodality management.

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsRadiosurgeryAgedCohort StudiesFemaleHumansMaleRetrospective StudiesTreatment Outcome

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.