Evidence map›Paper›PMID 38270741›Full record

ArticlePlant foods for human nutrition (Dordrecht, Netherlands)2024

Modulation Mechanism of Wuniuzao Dark Tea Polysaccharide on Lipid Metabolism in Hyperlipidemic Mice Induced by High-Fat Diet.

Xuanxuan Zou, Zonghua Dong, Wei Liu, Jin Zhao, Feng Guan, Jian Ge

Abstract read
PubMed Publisher
In one paragraph

Article in Plant foods for human nutrition (Dordrecht, Netherlands), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Xuanxuan Zou *College of Life Sciences, China Jiliang University, Hangzhou, Zhejiang, 310018, China.
Zonghua Dong *College of Life Sciences, China Jiliang University, Hangzhou, Zhejiang, 310018, China.
Wei LiuInstitute of Microbiology, Zhejiang Academy of Agricultural Sciences, Hangzhou, Zhejiang, 310021, China.
Jin ZhaoCollege of Life Sciences, China Jiliang University, Hangzhou, Zhejiang, 310018, China.
Feng GuanCollege of Life Sciences, China Jiliang University, Hangzhou, Zhejiang, 310018, China.
Jian GeCollege of Life Sciences, China Jiliang University, Hangzhou, Zhejiang, 310018, China. gejian@cjlu.edu.cn.
China Jiliang University · CNZheJiang Academy of Agricultural Sciences · CN

Funding

National Natural Science Foundation of China 31100499the Major Science and Technology Projects in Zhejiang Province 2020C02045
6 · The paper itself

Abstract

The aim of this study was to investigate the functional mechanism of Wuniuzao dark tea polysaccharide (WDTP) that protect against hyperlipidemia in mice induced by high-fat diet. WDTP was extracted by hot water, isolated and purified by DEAE-52 chromatography and characterized by high-performance liquid chromatograph (HPLC), Fourier transform infrared spectroscopy (FT-IR) and scanning electron microscope (SEM). Different doses (200 or 800 mg/kg/day) of WDTP were orally administered to mice induced by high-fat diet to evaluate the mechanism of WDTP regulating lipid metabolism. And these results showed that average molecular weight of WDTP was nearly 63,869 Da. And WDTP intervention significantly reduced body weight, lipid accumulation, and modulated blood lipid levels. The mechanism of WDTP ameliorating lipid metabolism was associated with regulating the expression of lipid metabolism-related genes and serum exosomes miR-19b-3p, and modulating the community structure of gut microbiota in mice.

Indexed as

HyperlipidemiasLipid MetabolismAnimalsDiet, High-FatLipidsMiceMice, Inbred C57BLSpectroscopy, Fourier Transform InfraredTeaLipidsTeaGut microbiotaLipid metabolismSerum exosomeWuniuzao dark tea polysaccharide

Identifiers

PMID38270741
OpenAlexW4391225635

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.