Evidence map›Paper›PMID 38270721›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2024

A secondary analysis: the impact of pre-existing chronic pain among patients with cancer presenting to the emergency department with acute pain.

Meghan Beck, Kristin L Schreiber, Jenna M Wilson, K Mikayla Flowers, Robert R Edwards, Peter R Chai, Desiree R Azizoddin

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In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 citations in OpenAlex.

  1. Symptom Networks in Postsurgical Cancer Pain Across Recovery Stages.Pain management nursing : official journal of the American Society of Pain Management Nurses · 2026
    Observational
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Meghan BeckDepartment of Anesthesiology, Perioperative, and Pain Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Kristin L SchreiberDepartment of Anesthesiology, Perioperative, and Pain Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Jenna M WilsonDepartment of Anesthesiology, Perioperative, and Pain Medicine, Brigham and Women's Hospital, Boston, MA, USA.
K Mikayla FlowersDepartment of Anesthesiology, Perioperative, and Pain Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Robert R EdwardsDepartment of Anesthesiology, Perioperative, and Pain Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Peter R ChaiDepartment of Emergency Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Desiree R AzizoddinDepartment of Emergency Medicine, Brigham and Women's Hospital, Boston, MA, USA. Desiree-azizoddin@ouhsc.edu.
Brigham and Women's Hospital · US

Funding

Personalizing Perioperative Preventive Analgesia: Translational Studies Investigating the Biopsychosocial Underpinnings of Enhanced Pain PropensityR35GM128691 · NIGMS · STANFORD UNIVERSITY · PI KRISTIN SCHREIBER · 2018 to 2026
$4.3M
Smart Steps: A context-aware adherence intervention to improve PrEP adherence among men who have sex with men (MSM) with substance use disorderDP2DA056107 · NIDA · BRIGHAM AND WOMEN'S HOSPITAL · PI CHAI, PETER R · 2022 to 2022
$2.7M
Development of Ingestible Biosensors to Enhance PrEP Adherence in Substance UsersK23DA044874 · NIDA · BRIGHAM AND WOMEN'S HOSPITAL · PI CHAI, PETER R · 2018 to 2022
$1.0M
Integrating pain-CBT into an mHealth analgesic support intervention for patients withchronic pain from advanced cancersK08CA266937 · NCI · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI Desiree R Hilton · 2022 to 2026
$1.0M
NCI NIH HHS K08 CA266937NCI NIH HHS L30 CA242493NIDA NIH HHS DP2 DA056107NIDA NIH HHS K23 DA044874NIGMS NIH HHS R35 GM128691
6 · The paper itself

Abstract

purposePatients with cancer may experience pain from cancer itself or its treatment. Additionally, chronic pain (CP) predating a patient's cancer diagnosis may make the etiology of pain less clear and the management of pain more complex. In this brief report, we investigated differences in biopsychosocial characteristics, pain severity, and opioid consumption, comparing groups of cancer patients with and without a history of CP who presented to the emergency department (ED) with a complaint of cancer-related pain.

methodsThis secondary analysis of a prospective cohort study included patients with cancer who presented to the ED with a complaint of pain (≥ 4/10). Sociodemographic, clinical, psychological, and pain characteristics were assessed in the ED and subsequent hospitalization. Mann-Whitney U-, T-, and Chi-square tests were used to compare differences between patients with and without pre-existing CP before cancer.

resultsPatients with pre-existing CP had lower income (p = 0.21) and less formal education (p = 0.25) and were more likely to have a diagnosis of depression or substance use disorder (p < 0.01). Patients with pre-existing CP reported significantly greater pain severity in the ED and during hospitalization compared to those without pre-existing CP (p < 0.05), despite receiving greater amounts of opioid analgesics (p = 0.036).

conclusionIdentifying a history of pre-existing CP during intake may help identify patients with cancer with difficult to manage pain, who may particularly benefit from multimodal interventions and supportive care. In addition, referral of these patients for the management of co-occurring pain disorders may help decrease the usage of the ED for undertreated pain.

Indexed as

Acute PainChronic PainNeoplasmsAnalgesics, OpioidEmergency Service, HospitalHumansProspective StudiesAnalgesics, OpioidAcute painCancerCancer painChronic PainEmergency departmentsHospitalizationOncologyOpioid analgesicsPain managementPain psychology

Identifiers

PMID38270721
PMCPMC11069411
OpenAlexW4391226694

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.