Evidence map›Paper›PMID 38270632›Full record

ArticleAnalytical and bioanalytical chemistry2024

Development of new matrix reference materials for quantitative urine analysis in drug tests.

Min Lv, Yujie Zhi, Liying Zhou, Zheng Qiao, Bin Di, Wei Liu, Hang Chen

Abstract read
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In one paragraph

Article in Analytical and bioanalytical chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Interpol review of forensic toxicology, 2023-2025.Forensic science international. Synergy · 2026
    Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Min LvDepartment of Forensic Toxicology, Shanghai Key Laboratory of Forensic Medicine, Academy of Forensic Science, No. 1347, Guangfu West Road, Putuo District, Shanghai, 200063, China.
Yujie ZhiDepartment of Forensic Toxicology, Shanghai Key Laboratory of Forensic Medicine, Academy of Forensic Science, No. 1347, Guangfu West Road, Putuo District, Shanghai, 200063, China.
Liying ZhouDepartment of Forensic Toxicology, Shanghai Key Laboratory of Forensic Medicine, Academy of Forensic Science, No. 1347, Guangfu West Road, Putuo District, Shanghai, 200063, China.
Zheng QiaoDepartment of Forensic Toxicology, Shanghai Key Laboratory of Forensic Medicine, Academy of Forensic Science, No. 1347, Guangfu West Road, Putuo District, Shanghai, 200063, China.
Bin DiSchool of Pharmacy, China Pharmaceutical University, No. 639, Longmian Avenue, Jiangning District, Nanjing, 211198, China.
Wei LiuDepartment of Forensic Toxicology, Shanghai Key Laboratory of Forensic Medicine, Academy of Forensic Science, No. 1347, Guangfu West Road, Putuo District, Shanghai, 200063, China.
Hang ChenDepartment of Forensic Toxicology, Shanghai Key Laboratory of Forensic Medicine, Academy of Forensic Science, No. 1347, Guangfu West Road, Putuo District, Shanghai, 200063, China. chenh@ssfjd.cn.

Funding

Ministry of Finance, PR China GY2021G-6National Key Research and Development Program of China 2022YFC3302005-1Shanghai Key Laboratory of Forensic 21DZ2270800
6 · The paper itself

Abstract

Accurate quantitative analyses require standardized methods to control and improve the analytical process in the laboratory. The availability of urine reference materials (RMs) may offer a feasible option to improve the accuracy of urine analysis and to control matrix effects. This paper presents the complete process of the development of matrix RMs in urine, including sample preparation, homogeneity, and stability studies, as well as uncertainty assessment. A freeze-drying process was developed, and freeze-dried human and pig urine samples were prepared and verified to have comparable homogeneity to liquid samples and higher stability than liquid human, pig, and artificial urine samples at 4℃ or room temperature and under extreme conditions. A total of 21 authentic urine samples from August 2022 were measured with freeze-dried RMs and spiked urine samples, and the reliability of the quantification of the RMs was compared. The freeze-dried human urine matrix RM appeared to be an excellent tool for daily quality control, as it showed high stability and gave the most consistent results with spiked samples.

Indexed as

Specimen HandlingUrinalysisAnimalsHumansReference StandardsReproducibility of ResultsSubstance Abuse DetectionSwineForensic toxicologyPig urineReference materialUrine analysis

Identifiers

PMID38270632

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.