Evidence map›Paper›PMID 38270622›Full record

ArticleArchives of gynecology and obstetrics2024

A novel predictive marker for placental abruption with composite adverse outcomes: creatinine-fibrinogen ratio.

Osman Onur Ozkavak, Atakan Tanacan, Murat Haksever, Refaettin Sahin, Duygu Tugrul Ersak, Eda Iskefiyeli, Dilek Sahin

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Article in Archives of gynecology and obstetrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Osman Onur OzkavakDepartment of Perinatology, Ankara Bilkent City Hospital, Cankaya, 06800, Ankara, Turkey. onurozkavakdr@gmail.com.ORCID 0000-0001-9259-7825
Atakan TanacanDepartment of Perinatology, Ankara Bilkent City Hospital, Cankaya, 06800, Ankara, Turkey.ORCID 0000-0001-8209-8248
Murat HakseverDepartment of Perinatology, Ankara Bilkent City Hospital, Cankaya, 06800, Ankara, Turkey.ORCID 0000-0002-9526-3828
Refaettin SahinDepartment of Perinatology, Ankara Bilkent City Hospital, Cankaya, 06800, Ankara, Turkey.ORCID 0000-0002-5866-1798
Duygu Tugrul ErsakDepartment of Perinatology, Ankara Bilkent City Hospital, Cankaya, 06800, Ankara, Turkey.ORCID 0000-0001-8591-8395
Eda IskefiyeliDepartment of Obstetrics and Gynaecology, Ankara Bilkent City Hospital, Ankara, Turkey.ORCID 0009-0003-6931-2467
Dilek SahinDepartment of Perinatology, Ankara Bilkent City Hospital, Cankaya, 06800, Ankara, Turkey.ORCID 0000-0001-8567-9048

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo develop a new cost-effective marker named creatinine-fibrinogen ratio (CFR) for the prediction of composite adverse outcomes (CAO) in placental abruption cases.

methodsA total of 109 placental abruption patients (30 with adverse outcomes, 79 without adverse outcomes) were enrolled in this retrospective cohort study. Patients with at least one of the features listed below were included in the abruption with CAO group: requirement of blood product transfusion (erythrocyte suspension, fresh frozen plasma, pooled thrombocyte, thrombocyte apheresis), development of acute kidney injury or disseminated intravascular coagulation, and need for intensive care unit. Laboratory parameters and CFR values at admission to the hospital were compared between the two groups.

resultsHigher creatinine and lower fibrinogen levels were found in the CAO group (p = 0.007 and p < 0.001 respectively). The CFR value of the CAO group was significantly higher (p < 0.001). In the ROC curve analysis performed to investigate the value of CFR in CAO prediction, the area under the curve (AUC) was calculated as 0,802 (95% CI 0.709-0.895, 77% sensitivity, 65% specificity).

conclusionCFR seems to be a practical marker for the prediction of CAOs in pregnant women with ablatio placenta.

Indexed as

Abruptio PlacentaeBiomarkersCreatinineFibrinogenAcute Kidney InjuryAdultBlood TransfusionDisseminated Intravascular CoagulationFemaleHumansPredictive Value of TestsPregnancyRetrospective StudiesROC CurveYoung AdultBiomarkersCreatinineFibrinogenCreatinine–fibrinogen ratioPlacental abruption

Identifiers

PMID38270622

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.