Evidence map›Paper›PMID 38270599›Full record

ArticleArchives of microbiology2024

Anti-microbial efficacy of a scientifically developed and standardized herbal-alcohol sanitizer.

Rajkumar Tulsawani, Kalyani Verma, Ekta Kohli, Purva Sharma, Yogesh Singh Meena, Amitabh, Sarkaraisamy Ponmariappan, Prashant Kumar, Rekha Maithani

Abstract read
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In one paragraph

Article in Archives of microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Rajkumar TulsawaniDefence Institute of Physiology and Allied Sciences (DIPAS), Lucknow Road, Timarpur, New Delhi, India. rktulsawani@yahoo.com.
Kalyani VermaDefence Institute of Physiology and Allied Sciences (DIPAS), Lucknow Road, Timarpur, New Delhi, India.
Ekta KohliDefence Institute of Physiology and Allied Sciences (DIPAS), Lucknow Road, Timarpur, New Delhi, India.
Purva SharmaDefence Institute of Physiology and Allied Sciences (DIPAS), Lucknow Road, Timarpur, New Delhi, India.
Yogesh Singh MeenaDefence Institute of Physiology and Allied Sciences (DIPAS), Lucknow Road, Timarpur, New Delhi, India.
AmitabhDefence Institute of Physiology and Allied Sciences (DIPAS), Lucknow Road, Timarpur, New Delhi, India.
Sarkaraisamy PonmariappanDefence Research and Development Establishment (DRDE), Jhansi Road, Gwalior, India.
Prashant KumarAmity Institute of Virology and Immunology (AIVI), Amity University, Sector-125, Noida, India.
Rekha MaithaniDefence Institute of Physiology and Allied Sciences (DIPAS), Lucknow Road, Timarpur, New Delhi, India.
Defence Institute of Physiology and Allied Sciences · INAmity University · INDefence Research and Development Establishment · IN

Funding

Defence Research and Development Organisation COVID19 Emergency Fund
6 · The paper itself

Abstract

Hands are the primary mode of transmission of microbe-based infections, as they harbor normal microbiota and pathogenic microbes. SARS-CoV-2 has endangered lives worldwide, and WHO has recommended good hygiene practices, especially hand hygiene. In addition, other infectious diseases like diphtheria, measles, tuberculosis, HIV, malaria, etc. are spreading in the shadow of the COVID-19 pandemic. The anti-microbial efficiency of two in-house developed herbal-alcohol based hand sanitizers containing Azadirachta indica, Citrus limon, Zingiber officinale, and Aloe vera (HS1) and Zingiber officinale replaced with Ocimum sanctum (HS2) was evaluated. HS1, with Zingiber officinale, and HS2, with Ocimum sanctum, herbal sanitizers showcased in-vitro anti-viral activity on MDCK cells using the reference strain of influenza A virus, A/PR/8/34 (H1N1), and reduced 99.99% of microbial load within 30 s of contact time, estimated by the Antimicrobial Susceptibility Testing Method. On volunteers, HS1 and HS2 were more effective than alcohol-based WHO sanitizers. Moreover, HS2 sanitizer is more effective against viruses and has better efficiency and hedonic qualities in volunteers than HS1. These sanitizers don't irritate or dry up the skin and have a longer shelf life. Overall, findings reveal that herbal-alcohol-based sanitizers are promising hand hygiene products with the capability of reducing microbial load.

Indexed as

CitrusCOVID-19Influenza A Virus, H1N1 SubtypeEthanolHumansPandemicsEthanolHand hygieneHerbal-alcohol sanitizersSARS-CoV-2WHO formulations

Identifiers

PMID38270599
OpenAlexW4391224484

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.