Evidence map›Paper›PMID 38270529›Full record

ArticleACS sensors2024

Rational Approach to Optimizing Conformation-Switching Aptamers for Biosensing Applications.

Monica Wolfe, Alyssa Cramer, Sean Webb, Eva Goorskey, Yaroslav Chushak, Peter Mirau, Netzahualcóyotl Arroyo-Currás, Jorge L Chávez

Abstract read
In one paragraph

Article in ACS sensors, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
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  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Generalizable Molecular Switch Designs forAccounts of chemical research · 2025
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Monica Wolfe711th Human Performance Wing, Air Force Research Laboratory, WPAFB, Ohio 45433, United States.ORCID 0000-0002-0506-6768
Alyssa Cramer711th Human Performance Wing, Air Force Research Laboratory, WPAFB, Ohio 45433, United States.ORCID 0000-0003-2997-5066
Sean Webb711th Human Performance Wing, Air Force Research Laboratory, WPAFB, Ohio 45433, United States.
Eva Goorskey711th Human Performance Wing, Air Force Research Laboratory, WPAFB, Ohio 45433, United States.
Yaroslav Chushak711th Human Performance Wing, Air Force Research Laboratory, WPAFB, Ohio 45433, United States.
Peter MirauMaterials and Manufacturing Directorate, Air Force Research Laboratory, WPAFB, Ohio 45433, United States.ORCID 0000-0002-5210-4990
Netzahualcóyotl Arroyo-CurrásDepartment of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, United States.ORCID 0000-0002-2740-6276
Jorge L Chávez711th Human Performance Wing, Air Force Research Laboratory, WPAFB, Ohio 45433, United States.ORCID 0000-0002-0771-6947

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The utilization of structure-switching aptamers (SSAs) has enabled the development of novel sensing platforms for the sensitive and continuous detection of molecules.

Indexed as

Aptamers, NucleotideBiosensing TechniquesHumansHydrocortisoneNucleic Acid ConformationAptamers, NucleotideHydrocortisoneaptamersbiosensorscortisolmicroarrayNMRsequence optimizationstressstructure-switching

Identifiers

PMID38270529
PMCPMC10897929

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.