Evidence map›Paper›PMID 38270456›Full record

ArticlemSystems2024

Temporal genome-wide fitness analysis of

Louise H Lefrançois, Jahn Nitschke, Huihai Wu, Gaël Panis, Julien Prados, Rachel E Butler, Tom A Mendum, Nabil Hanna, Graham R Stewart, Thierry Soldati

Open access · goldAbstract read
In one paragraph

Article in mSystems, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Frontiers in immunology · 2026
    Review
  5. Article
  6. SMURF2 inhibits autophagic control ofbioRxiv : the preprint server for biology · 2025
    Article
  7. Article
  8. Cell biology of Dictyostelium.BMC molecular and cell biology · 2025
    Article
  9. Article
  10. Frontiers in microbiology · 2025
    Article
  11. Review
  12. Discovery of anti-infective compounds againstFrontiers in microbiology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Louise H Lefrançois *Department of Biochemistry, Faculty of Science, University of Geneva, Science II, Geneva, Switzerland.ORCID 0000-0002-9544-8435
Jahn Nitschke *Department of Biochemistry, Faculty of Science, University of Geneva, Science II, Geneva, Switzerland.ORCID 0000-0003-3838-0945
Huihai WuDepartment of Microbial Sciences, School of Biosciences, University of Surrey, Guildford, Surrey, United Kingdom.
Gaël PanisDepartment of Microbiology and Molecular Medicine, Faculty of Medicine/CMU, University of Geneva, Institute of Genetics and Genomics in Geneva (iGE3), Genève, Switzerland.ORCID 0000-0002-6926-6224
Julien PradosDepartment of Microbiology and Molecular Medicine, Faculty of Medicine/CMU, University of Geneva, Institute of Genetics and Genomics in Geneva (iGE3), Genève, Switzerland.ORCID 0000-0002-8546-241X
Rachel E ButlerDepartment of Microbial Sciences, School of Biosciences, University of Surrey, Guildford, Surrey, United Kingdom.ORCID 0000-0002-6018-7765
Tom A MendumDepartment of Microbial Sciences, School of Biosciences, University of Surrey, Guildford, Surrey, United Kingdom.ORCID 0000-0002-6331-2605
Nabil HannaDepartment of Biochemistry, Faculty of Science, University of Geneva, Science II, Geneva, Switzerland.ORCID 0000-0002-3288-5486
Graham R StewartDepartment of Microbial Sciences, School of Biosciences, University of Surrey, Guildford, Surrey, United Kingdom.ORCID 0000-0002-6867-6248
Thierry SoldatiDepartment of Biochemistry, Faculty of Science, University of Geneva, Science II, Geneva, Switzerland.ORCID 0000-0002-2056-7931
University of Geneva · CHUniversity of Surrey · GB

Funding

National Centre for the Replacement Refinement and Reduction of Animals in Research (NC3Rs) NC/M002012/1Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (SNF) 310030_169386Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (SNF) 310030_188813SystemsX.ch (Swiss SystemsX.ch) HostPathX
6 · The paper itself

Abstract

Tuberculosis remains the most pervasive infectious disease and the recent emergence of drug-resistant strains emphasizes the need for more efficient drug treatments. A key feature of pathogenesis, conserved between the human pathogen

Indexed as

AmoebaDictyosteliumMycobacterium marinumMycobacterium tuberculosisTuberculosisAnimalsHumansLipidsMiceMicrogliaVirulenceLipidsBV2 microglial cellsDictyostelium discoideumessentialityMycobacterium marinumphenotypic profilingTn-Seq

Identifiers

PMID38270456
PMCPMC10878075
OpenAlexW4391230486

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.