Evidence map›Paper›PMID 38270209›Full record

ArticleEmerging infectious diseases2023

Piscichuvirus-Associated Severe Meningoencephalomyelitis in Aquatic Turtles, United States, 2009-2021.

Weerapong Laovechprasit, Kelsey T Young, Brian A Stacy, Steven B Tillis, Robert J Ossiboff, Jordan A Vann, Kuttichantran Subramaniam, Dalen W Agnew, Elizabeth W Howerth, Jian Zhang and 8 more

Open access · diamondAbstract read
In one paragraph

Article in Emerging infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Weerapong Laovechprasit
Kelsey T Young
Brian A Stacy
Steven B Tillis
Robert J Ossiboff
Jordan A Vann
Kuttichantran Subramaniam
Dalen W Agnew
Elizabeth W Howerth
Jian Zhang
Shayna Whitaker
Alicia Walker
Andrew M Orgill
Lyndsey N Howell
Donna J Shaver
Kyle Donnelly
Allen M Foley
James B Stanton

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viruses from a new species of piscichuvirus were strongly associated with severe lymphocytic meningoencephalomyelitis in several free-ranging aquatic turtles from 3 coastal US states during 2009-2021. Sequencing identified 2 variants (freshwater turtle neural virus 1 [FTuNV1] and sea turtle neural virus 1 [STuNV1]) of the new piscichuvirus species in 3 turtles of 3 species. In situ hybridization localized viral mRNA to the inflamed region of the central nervous system in all 3 sequenced isolates and in 2 of 3 additional nonsequenced isolates. All 3 sequenced isolates phylogenetically clustered with other vertebrate chuvirids within the genus Piscichuvirus. FTuNV1 and STuNV1 shared ≈92% pairwise amino acid identity of the large protein, which narrowly places them within the same novel species. The in situ association of the piscichuviruses in 5 of 6 turtles (representing 3 genera) with lymphocytic meningoencephalomyelitis suggests that piscichuviruses are a likely cause of lymphocytic meningoencephalomyelitis in freshwater and marine turtles.

Indexed as

TurtlesAnimalsCentral Nervous SystemRNA, MessengerUnited StatesRNA, Messengerencephalomyelitisinfectious diseasesmeningitis/encephalitismeningoencephalomyelitismetagenomicsPiscichuvirusturtlesUnited Statesviruses

Identifiers

PMID38270209
PMCPMC10826744
OpenAlexW4390830046

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.