Article in American journal of physiology. Renal physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.
0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Jessica Paola Bahena-LopezDepartment of Nephrology and Mineral Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Laura VergaraUnidad de Investigación UNAM-INCICH, Instituto Nacional de Cardiología Ignacio Chávez and Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Mexico City, Mexico.ORCID 0009-0008-9472-0805
Valeria de la-PeñaDepartment of Nephrology and Mineral Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.ORCID 0009-0004-6022-9293
Miguel A Gutierrez-GallardoDepartment of Nephrology and Mineral Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.ORCID 0009-0008-2468-6488
Paulina López-IbargüenDepartment of Nephrology and Mineral Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Janeth Alejandra GarcíaMolecular Physiology Unit, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Mexico City, Mexico.ORCID 0009-0008-6647-6235
Héctor Carbajal-ContrerasDepartment of Nephrology and Mineral Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Norma VázquezMolecular Physiology Unit, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Mexico City, Mexico.ORCID 0000-0002-5265-9929
Ruth Rincón-HerediaUnidad de Imagenología, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico City, Mexico.ORCID 0000-0002-5070-938X
Felipe MassoUnidad de Investigación UNAM-INCICH, Instituto Nacional de Cardiología Ignacio Chávez and Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Mexico City, Mexico.ORCID 0000-0001-8671-3367
Norma A BobadillaDepartment of Nephrology and Mineral Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.ORCID 0000-0002-3153-9151
María Castañeda-BuenoDepartment of Nephrology and Mineral Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.ORCID 0000-0002-5801-3504
David H EllisonDivision of Nephrology and Hypertension, Department of Medicine, Oregon Health and Science University, Portland, Oregon, United States.ORCID 0000-0003-2915-265X
Gerardo GambaDepartment of Nephrology and Mineral Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.ORCID 0000-0002-4378-9043
María Chávez-CanalesUnidad de Investigación UNAM-INCICH, Instituto Nacional de Cardiología Ignacio Chávez and Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Mexico City, Mexico.ORCID 0000-0002-2090-3691
Funding
WNK Kinase Regulation of Thiazide-sensitive NaCl TransportR01DK051496 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI David Hoadley Ellison, CHAO-LING YANG · 1998 to 2026
$8.4M
Consejo Nacional de Ciencia y Tecnología (CONACYT) 87794Foundation for the National Institutes of Health (FNIH) DK51496NIDDK NIH HHS R01 DK051496UNAM | Dirección General de Asuntos del Personal Académico, Universidad Nacional Autónoma de México (DGAPA) IA208522UNAM | Dirección General de Asuntos del Personal Académico, Universidad Nacional Autónoma de México (DGAPA) IN203422
6 · The paper itself
Abstract
Kidney-specific with-no-lysine kinase 1 (KS-WNK1) is an isoform of WNK1 kinase that is predominantly found in the distal convoluted tubule of the kidney. The precise physiological function of KS-WNK1 remains unclear. Some studies have suggested that it could play a role in regulating potassium renal excretion by modulating the activity of the Na
Indexed as
Mice, KnockoutPotassium, DietaryWNK Lysine-Deficient Protein Kinase 1AnimalsFemaleKidneyKidney Tubules, DistalMaleMiceMice, Inbred C57BLPhosphorylationPotassiumProtein Serine-Threonine KinasesRenal EliminationSolute Carrier Family 12, Member 3PotassiumPotassium, DietaryProtein Serine-Threonine KinasesSlc12a3 protein, mouseSolute Carrier Family 12, Member 3Wnk1 protein, mouseWNK Lysine-Deficient Protein Kinase 1distal convoluted tubuleNa+-Cl– cotransporterpotassium renal excretionwith-no-lysine kinase
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
KS-WNK1 is required for the renal response to extreme changes in potassium intake. · full record | OpenQuestion