Evidence map›Paper›PMID 38269050›Full record

ArticleOpen forum infectious diseases2024

Reflex Human Immunodeficiency Virus (HIV) Type 1 RNA Testing Enables Timely Differentiation of False-Positive Results From Acute HIV Infection.

Christopher Kaperak, Dylan Eller, Samantha A Devlin, André Hall, Jessica Schmitt, Eleanor E Friedman, Kathleen G Beavis, Kimberly A Stanford, David Pitrak, Moira C McNulty

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Different approaches to HIV confirmation: a survey of three Italian regions.Frontiers in cellular and infection microbiology · 2026
    Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Christopher KaperakDepartment of Medicine, University of Chicago Medicine, Chicago, Illinois, USA.
Dylan EllerSection of Infectious Diseases and Global Health, University of Chicago, Chicago, Illinois, USA.
Samantha A DevlinSection of Infectious Diseases and Global Health, University of Chicago, Chicago, Illinois, USA.
André HallSection of Infectious Diseases and Global Health, University of Chicago, Chicago, Illinois, USA.
Jessica SchmittSection of Infectious Diseases and Global Health, University of Chicago, Chicago, Illinois, USA.
Eleanor E FriedmanSection of Infectious Diseases and Global Health, University of Chicago, Chicago, Illinois, USA.
Kathleen G BeavisDepartment of Pathology, University of Chicago, Chicago, Illinois, USA.
Kimberly A StanfordSection of Emergency Medicine, University of Chicago, Chicago, Illinois, USA.
David PitrakSection of Infectious Diseases and Global Health, University of Chicago, Chicago, Illinois, USA.
Moira C McNultySection of Infectious Diseases and Global Health, University of Chicago, Chicago, Illinois, USA.ORCID https://orcid.org/0000-0002-9651-254X
University of Chicago · US

Funding

Implementation of emergency department screening to impact rising syphilis rates in vulnerable populationsK23AI166277 · NIAID · UNIVERSITY OF CHICAGO · PI STANFORD, KIMBERLY · 2022 to 2025
$820k
NIAID NIH HHS K23 AI166277
6 · The paper itself

Abstract

Accurate, timely human immunodeficiency virus (HIV) diagnosis is critical. Routine HIV screening program data were examined before and after reflex HIV type 1 RNA testing. Reflex testing facilitated confirmation of reactive HIV screening assays (as true or false positives) (odds ratio, 23.7 [95% confidence interval, 6.7-83.4];

Indexed as

acute HIV infectiondiscordant resultsHIV testingreflex HIV-1 RNA

Identifiers

PMID38269050
PMCPMC10807991
OpenAlexW4389612391

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.