ArticleFood science & nutrition2024
Mixture design of α-pinene, α-terpineol, and 1,8-cineole: A multiobjective response followed by chemometric approaches to optimize the antibacterial effect against various bacteria and antioxidant activity.
Article in Food science & nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 30 citations in OpenAlex.
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- Cardamom Essential Oil Exerts a Curative Effect Against Kiwifruit Bacterial Canker but Fails to Activate Host Defense Mechanisms.Plants (Basel, Switzerland) · 2026Article
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- Optimizing Essential Oil Blends by Mixture Design Approaches for Enhanced Antimicrobial and Antioxidant Activity: A Review.Journal of food science · 2026Review
- Antibacterial potential and in silico analysis of inflorescence-derived essential oils from three Eucalyptus species.Scientific reports · 2025Article
- Harnessing Pelargonium Odoratissimum Extracts for Sustainable Ground Meat Preservation.Journal of food science · 2025Article
- Clove, Cinnamon, and Peppermint Essential Oils as Antibiofilm Agents AgainstMolecules (Basel, Switzerland) · 2025Article
- Antibacterial Activity and Chemical Composition of Popular Plant Essential Oils and Their Positive Interactions in Combination.Molecules (Basel, Switzerland) · 2025Article
- Study ofFrontiers in plant science · 2025Article
- Volatiles extracted from Melaleuca Rugulosa (Link) Craven leaves: comparative profiling, bioactivity screening, and metabolomic analysis.BMC complementary medicine and therapies · 2024Article
- Insight intoFoods (Basel, Switzerland) · 2024Article
- Enhancing Antibacterial Efficacy: Synergistic Effects ofFoods (Basel, Switzerland) · 2024Article
- Effects of intrinsic and extrinsic growth factors on virulence gene expression of foodborne pathogens in vitro and in food model systems; a review.Food science & nutrition · 2024Review
- Phytochemical Analysis and Antioxidant and Antifungal Activities of Powders, Methanol Extracts, and Essential Oils fromInternational journal of molecular sciences · 2024Article
- GC-MS analysis, phytochemical composition ofRSC advances · 2024Article
- Mixture design of α-pinene, α-terpineol, and 1,8-cineole: A multiobjective response followed by chemometric approaches to optimize the antibacterial effect against various bacteria and antioxidant activity.Food science & nutrition · 2024Article
Corrections and comments
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Authors and funding
10 authors at 8 institutions in 6 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
α-Pinene, α-terpineol, and 1,8-cineole are compounds naturally present in essential oils, although their amounts vary from oil to oil. Although several studies have reported their antibacterial and antioxidant effects, there are few reports on the synergistic or antagonistic effects of their combinations. The objective of this study was to investigate the combined antibacterial effect of these three compounds. To our knowledge, this is the first report on the prediction of their optimal combination using the mixture design approach. The experimental antibacterial activity of the α-pinene, α-terpineol, and 1,8-cineole mixtures depended on the proportion of each compound in the mixture and the target strain, with minimum inhibitory concentrations (MIC) ranging from 0.31 to 1.85 mg/mL. Using the increased simplex-centroid mixture design, the mixture containing 0.33% of each molecule proved to be the most effective against
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.