Evidence map›Paper›PMID 38268771›Full record

ArticleOrganic process research & development2024

Process Development for the Manufacture of the Antimalarial Amodiaquine Dihydrochloride Dihydrate.

Mukut Gohain, Modibo S Malefo, Phaladi Kunyane, Chantal Scholtz, Sangeeta Baruah, Andile Zitha, Gerrit van der Klashorst, Hannes Malan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Organic process research & development, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mukut GohainDepartment of Research and Development at Chemical Process Technologies (Pty) Ltd, 45 Battery Crescent, Waltloo, City of Tshwane, Gauteng 0184, South Africa.ORCID https://orcid.org/0000-0002-9308-0825
Modibo S MalefoDepartment of Research and Development at Chemical Process Technologies (Pty) Ltd, 45 Battery Crescent, Waltloo, City of Tshwane, Gauteng 0184, South Africa.
Phaladi KunyaneDepartment of Research and Development at Chemical Process Technologies (Pty) Ltd, 45 Battery Crescent, Waltloo, City of Tshwane, Gauteng 0184, South Africa.
Chantal ScholtzDepartment of Research and Development at Chemical Process Technologies (Pty) Ltd, 45 Battery Crescent, Waltloo, City of Tshwane, Gauteng 0184, South Africa.ORCID https://orcid.org/0000-0002-3321-7121
Sangeeta BaruahDepartment of Research and Development at Chemical Process Technologies (Pty) Ltd, 45 Battery Crescent, Waltloo, City of Tshwane, Gauteng 0184, South Africa.
Andile ZithaDepartment of Research and Development at Chemical Process Technologies (Pty) Ltd, 45 Battery Crescent, Waltloo, City of Tshwane, Gauteng 0184, South Africa.
Gerrit van der KlashorstDepartment of Research and Development at Chemical Process Technologies (Pty) Ltd, 45 Battery Crescent, Waltloo, City of Tshwane, Gauteng 0184, South Africa.
Hannes MalanDepartment of Research and Development at Chemical Process Technologies (Pty) Ltd, 45 Battery Crescent, Waltloo, City of Tshwane, Gauteng 0184, South Africa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A robust process for the manufacture of the active pharmaceutical ingredient (API) amodiaquine dihydrochloride dihydrate (ADQ,

Identifiers

PMID38268771
PMCPMC10804403

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.