Evidence map›Paper›PMID 38268466›Full record

ArticleNeurorehabilitation and neural repair2024

Patient Outcomes After Peripheral Nerve Injury Depend on Bimanual Dexterity and Preserved Use of the Affected Hand.

Taewon Kim, Keith R Lohse, Susan E Mackinnon, Benjamin A Philip

Abstract read
In one paragraph

Article in Neurorehabilitation and neural repair, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Taewon KimProgram in Occupational Therapy, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0001-6870-4379
Keith R LohseProgram in Physical Therapy, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0002-7643-3887
Susan E MackinnonDivision of Plastic and Reconstructive Surgery, Washington University School of Medicine, St. Louis, MO, USA.
Benjamin A PhilipProgram in Occupational Therapy, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0001-5467-8384

Funding

Interhemispheric Communication and Compensation in Peripheral Nerve InjuryR01NS114046 · NINDS · WASHINGTON UNIVERSITY · PI EGGEBRECHT, ADAM THOMAS · 2021 to 2025
$2.1M
NINDS NIH HHS R01 NS114046
6 · The paper itself

Abstract

backgroundLittle is known about how peripheral nerve injury affects human performance, behavior, and life. Hand use choices are important for rehabilitation after unilateral impairment, but rarely measured, and are not changed by the normal course of rehabilitation and daily life.

objectiveTo identify the relationship between hand use (L/R choices), motor performance, and patient-centered outcomes.

methodsParticipants (n = 48) with unilateral peripheral nerve injury were assessed for hand use via Block Building Task, Motor Activity Log, and Edinburgh Handedness Inventory; dexterity (separately for each hand) via Nine-Hole Peg Test, Jebsen Taylor Hand Function Test, and a precision drawing task; patient-centered outcomes via surveys of disability, activity participation, and health-related quality of life; and injury-related factors including injury cause and affected nerve. Factor Analysis of Mixed Data was used to explore relationships between these variables. The data were analyzed under 2 approaches: comparing dominant hand (DH) versus non-dominant hand (NH), or affected versus unaffected hand.

resultsThe data were best explained by 5 dimensions. Good patient outcomes were associated with NH performance, DH performance (separately and secondarily to NH performance), and preserved function and use of the affected hand; whereas poor patient outcomes were associated with preserved but unused function of the affected hand.

conclusionAfter unilateral peripheral nerve injury, hand function, hand usage, and patient life arise from a complex interaction of many factors. To optimize rehabilitation after unilateral impairment, new rehabilitation methods are needed to promote performance and use with the NH, as well as the injured hand.

Indexed as

Peripheral Nerve InjuriesFunctional LateralityHandHumansQuality of LifeUpper Extremityhand dominancelateralizationmanual dexterityperipheral nerve injuryquality of life

Identifiers

PMID38268466
PMCPMC10922924

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.