Evidence map›Paper›PMID 38268449›Full record

Trial reportHaematologica2024

Genomic landscape of patients in a phase II study of zanubrutinib in ibrutinib- and/or acalabrutinib-intolerant patients with B-cell malignancies.

Linlin Xu, Mazyar Shadman, Ian W Flinn, Moshe Y Levy, Ryan Porter, John M Burke, Syed F Zafar, Jennifer L Cultrera, Jamal Misleh, Edwin C Kingsley and 13 more

Abstract readClinical Trial, Phase II
In one paragraph

Trial report in Haematologica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

23 authors.

Linlin XuBeiGene (Beijing) Co., Ltd., Beijing, China and BeiGene USA, Inc., San Mateo, CA. Linlin.Xu@beigene.com.
Mazyar ShadmanFred Hutchinson Cancer Research Center, University of Washington, Seattle, WA.
Ian W FlinnSarah Cannon Research Institute/Tennessee Oncology, Nashville, TN.
Moshe Y LevyTexas Oncology Baylor Charles A. Sammons Cancer Center, Dallas, TX.
Ryan PorterSSM Health Dean Medical Group, Madison, WI.
John M BurkeRocky Mountain Cancer Centers, Aurora, CO.
Syed F ZafarFlorida Cancer Specialists and Research Institute, Fort Myers, FL.
Jennifer L CultreraFlorida Cancer Specialists and Research Institute, Leesburg, FL.
Jamal MislehMedical Oncology Hematology Consultants PA, Newark, DE.
Edwin C KingsleyComprehensive Cancer Centers of Nevada, Las Vegas, NV.
Habte A YimerTexas Oncology, Tyler, TX.
Benjamin FreemanSummit Medical Group, Florham Park, NJ.
Arvind ChaudhrySummit Cancer Centers, Spokane, WA.
Praveen K TumulaTexas Oncology, Amarillo, TX.
Mitul D GandhiVirginia Cancer Specialists, Gainesville, VA.
Rocco CrescenzoBeiGene (Beijing) Co., Ltd., Beijing, China and BeiGene USA, Inc., San Mateo, CA.
Kunthel ByBeiGene (Beijing) Co., Ltd., Beijing, China and BeiGene USA, Inc., San Mateo, CA.
Aileen CohenBeiGene (Beijing) Co., Ltd., Beijing, China and BeiGene USA, Inc., San Mateo, CA.
Dih-Yih ChenBeiGene (Beijing) Co., Ltd., Beijing, China and BeiGene USA, Inc., San Mateo, CA.
Adam IdoineBeiGene (Beijing) Co., Ltd., Beijing, China and BeiGene USA, Inc., San Mateo, CA.
Sudhir MandaArizona Oncology / US Oncology Research, Tucson, AZ, USA; and.
Jeff P SharmanWillamette Valley Cancer Institute and Research Center, Eugene, OR.
Vanitha RamakrishnanBeiGene (Beijing) Co., Ltd., Beijing, China and BeiGene USA, Inc., San Mateo, CA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdenineBenzamidesPiperidinesPyrazinesPyrazolesPyrimidinesAgedAminobutyratesFemaleGenomicsHumansLeukemia, Lymphocytic, Chronic, B-CellMaleMiddle AgedMutationProtein Kinase InhibitorsacalabrutinibAdenineAminobutyratesBenzamidesibrutinibPiperidinesProtein Kinase InhibitorsPyrazinesPyrazolesPyrimidinesSulfonamidesThiazoleszanubrutinib

Identifiers

PMID38268449
PMCPMC11215392

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.