Evidence map›Paper›PMID 38268289›Full record

SynthesisNursing open2024

Heparin versus normal saline for the care of peripheral intravenous catheters in children: A meta-analysis.

Weiying Zhang, Biqiong Wei, Mengqi Chai, Dan Chen

Open access · goldAbstract readMeta-Analysis
In one paragraph

Synthesis in Nursing open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Weiying ZhangDepartment of Emergency, Children's Hospital of Nanjing Medical University, Nanjing, China.
Biqiong WeiDepartment of Emergency, Children's Hospital of Nanjing Medical University, Nanjing, China.
Mengqi ChaiDepartment of Emergency, Children's Hospital of Nanjing Medical University, Nanjing, China.
Dan ChenDepartment of Emergency, Children's Hospital of Nanjing Medical University, Nanjing, China.ORCID 0009-0007-4942-4639
Nanjing Children's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo conduct a meta-analysis to evaluate the role of heparin versus normal saline lock in the care of peripheral intravenous catheters.

designA meta-analysis.

methodsThis meta-analysis searched nine databases for randomized controlled trials (RCTs) on heparin versus normal saline for the care of peripheral intravenous catheters in children up to April 5, 2023. The quality of included RCTs was evaluated using the risk of bias tool of Cochrane library. RevMan5.3 software was used for data analysis.

resultsTen RCTs with a total of 1255 children were involved. Meta-analysis indicated that heparin lock reduced the incidence of blockage of peripheral intravenous catheter [OR = 2.01, 95% CI (1.42,2.84), p < 0.001], prolonged the duration of peripheral intravenous catheter indwelling[MD = -0.43, 95% CI (-0.75, -0.11), p = 0.008]. There were no statistical differences in the incidence of phlebitis [OR = 1.02, 95% CI (0.59, 1.74), p = 0.95 W]. PUBLIC CONTRIBUTION: Heparin may have more benefits in the nursing care of peripheral intravenous catheters compared with normal saline.

Indexed as

HeparinSaline SolutionVascular Access DevicesChildData AnalysisHumansHeparinSaline Solutioncarechildrenheparinnormal salinenursingperipheral intravenous catheters

Identifiers

PMID38268289
PMCPMC10697116
OpenAlexW4389196807

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.