ArticleAnimal microbiome2024
Dietary Bacillus spp. supplementation to both sow and progenies improved post-weaning growth rate, gut function, and reduce the pro-inflammatory cytokine production in weaners challenged with Escherichia coli K88.
Article in Animal microbiome, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 8 citations in OpenAlex.
- Phenotypic and Genomic Analysis of Swine-DerivedAnimals : an open access journal from MDPI · 2026Article
- Effects of Compound Probiotics on Production Performance, Apparent Digestion Rate of Nutrients and Serum Index of Pigs at Different Stages.Animals : an open access journal from MDPI · 2026Article
- Probiotics and enzymes in weaned piglets' diets can lower belly nosing frequency and improve performance and nitrogen balance.Tropical animal health and production · 2026Article
- Effects of Multi-Strain Probiotic Supplementation in Low-Crude Protein Diets on Growth Performance, Apparent Nutrient Digestibility, Fecal Microbial Indicators, and Nitrogen Utilization in Weaned Piglets.Animals : an open access journal from MDPI · 2026Article
- Probiotics as antioxidant, antistress, and growth-enhancing agents in monogastric animals: a narrative review.Frontiers in veterinary science · 2026Review
- Impact of Maternal Parity and Direct-Fed Microbial Supplementation on Reproductive Performance, Digestibility, and Milk Quality from Early Gestation to Lactation in Sows.Animals : an open access journal from MDPI · 2025Article
- The Role of Nutrition Across Production Stages to Improve Sow Longevity.Animals : an open access journal from MDPI · 2025Review
- Alleviating peripartum oxidative stress and enhancing maternal behavior in loose-housed hyperprolific sows improves the farrowing process and piglet performance: effects of ferulic acid, probiotic mixture, or jute sacks.Journal of animal science · 2025Article
- Article
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Corrections and comments
- Erratum issued
Authors and funding
11 authors at 1 institution in 1 country.
Funding
Abstract
backgroundThe use of probiotics (PRO) in late gestation sow and their impact on progenies' performance during the post-weaning stage has received more attention from the researchers recently. This study aimed to analyze the effect of probiotic mixture (Bacillus subtilis and Bacillus licheniformis) on both sow and offspring's performance.
methodsFirst experiment (Exp.1) was conducted from the 100th day of gestation through to post-weaning. A total of twenty sows and their litters were assigned to one of two dietary treatments, Control (CON) based diet and PRO- CON+ 0.05% probiotic mixture. Dietary treatments were arranged in a split-plot pattern with sow and weaner treatment (CON and PRO diet) as the main and sub plot. Exp.2. E. coli challenge study was carried out two weeks after weaning with 40 piglets. Dietary treatments remained same while all pigs were orally administered with a 1.5 ml suspension of 1010 CFU of K88 strain of E. coli per ml.
resultPRO group sow showed significantly decreased backfat thickness difference and body weight difference after farrowing and at the end of weaning d21. The nutrient digestibility of PRO group sows was significantly higher at the end of weaning. Moreover, piglets born from PRO group sow showed higher weaning weight and tend to increase average daily gain at the end of d21. The addition of mixed probiotic in sow and weaner diet had suppressed the production of TNF-α and interleukin-6 in E. coli challenged pigs. The phyla Firmicutes and Bacteroidetes in E. coli -challenged pigs were highly abundant while, the relative abundance of clostridium_sensu_stricto_1 at genus level was significantly reduced by the inclusion of probiotic in both the sow and weaner diet. Also, taxonomic distribution analysis showed significantly lower prevalence of Clostridium and Brachyspira and higher prevalence of Lactobacilli in E. coli-challenged pigs that were born from PRO group sow and fed CON and PRO weaner diet.
conclusionThis study reveals that the inclusion of 0.05% mixed probiotics (Bacillus spp.) to both sow and their progenies diet would be more beneficial to enhance the post-weaning growth rate, gut health, and immune status of E. coli challenged pigs.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.