Evidence map›Paper›PMID 38267960›Full record

ArticleParasites & vectors2024

Demodicosis in a Kunekune pig and molecular characterisation of porcine demodectic mites involved: a case report.

Lukas Schwarz, Verena Herb, Sophie Dürlinger, Vera Martin, Nina Poláková, Christa Horvath-Ungerböck, Rene Brunthaler, Christian Knecht, Maximiliane Dippel, Jutta Pikalo and 3 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Parasites & vectors, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Parasite diversity in grey wolves (International journal for parasitology. Parasites and wildlife · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Lukas SchwarzDepartment for Farm Animals and Veterinary Public Health, University Clinic for Swine, University of Veterinary Medicine Vienna, Vienna, Austria. lukas.schwarz@vetmeduni.ac.at.
Verena HerbClinical Unit of Small Animal Surgery, Ophthalmology, Department for Companion Animals and Horses, University Clinic for Small Animals, University of Veterinary Medicine Vienna, Vienna, Austria.
Sophie DürlingerDepartment for Farm Animals and Veterinary Public Health, University Clinic for Swine, University of Veterinary Medicine Vienna, Vienna, Austria.
Vera MartinDepartment for Farm Animals and Veterinary Public Health, University Clinic for Swine, University of Veterinary Medicine Vienna, Vienna, Austria.
Nina PolákováClinical Unit of Internal Medicine Small Animals, Dermatology, Department for Companion Animals and Horses, University Clinic for Small Animals, University of Veterinary Medicine Vienna, Vienna, Austria.
Christa Horvath-UngerböckClinical Unit of Internal Medicine Small Animals, Dermatology, Department for Companion Animals and Horses, University Clinic for Small Animals, University of Veterinary Medicine Vienna, Vienna, Austria.
Rene BrunthalerDepartment of Pathobiology, Institute of Pathology, University of Veterinary Medicine Vienna, Vienna, Austria.
Christian KnechtDepartment for Farm Animals and Veterinary Public Health, University Clinic for Swine, University of Veterinary Medicine Vienna, Vienna, Austria.
Maximiliane DippelDepartment for Farm Animals and Veterinary Public Health, University Clinic for Swine, University of Veterinary Medicine Vienna, Vienna, Austria.
Jutta PikaloDepartment of Pathobiology, Institute of Parasitology, University of Veterinary Medicine Vienna, Vienna, Austria.
Andrea LadinigDepartment for Farm Animals and Veterinary Public Health, University Clinic for Swine, University of Veterinary Medicine Vienna, Vienna, Austria.
Anja JoachimDepartment of Pathobiology, Institute of Parasitology, University of Veterinary Medicine Vienna, Vienna, Austria.
Hans-Peter FuehrerDepartment of Pathobiology, Institute of Parasitology, University of Veterinary Medicine Vienna, Vienna, Austria.
University of Veterinary Medicine Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn January 2021, a female 1-year-old Kunekune was presented at the University Clinic for Swine with severe reduction of the field of vision resulting in prolonged reaction time when targeting barriers, due to moderate to severe thickening of the skin around both orbits also affecting the eyelids.

methodsClinical examination revealed skin hyperplasia, nodular enlargement of the skin pores of the axillar and inguinal region. Ophthalmologists decided to remove parts of the thickened periocular skin, followed by histopathological examination.

resultsOnce large amounts of demodectic mites were detected by histopathology, demodicosis could be diagnosed and treatment of the pig was started using sarolaner. Morphological and molecular analyses were performed. Histopathological and parasitological exams led to the aetiological diagnosis of demodicosis in the affected Kunekune pig. Severe skin lesions were revealed to be the consequence of an infestation with Demodex sp. Morphological analyses confirmed the involvement of D. phylloides. Molecular characterization indicated a Demodex species closely related to mites documented in wild boar - most probably D. phylloides for which no explicit sequences are available in GenBank yet. Treatment with sarolaner (2.6 mg/kg) resulted in a substantial regression of skin lesions, already detectable 1 month after first treatment.

conclusionsDemodicosis is a very rare disease in pigs that is most probably related to an impaired immune response to the mites. Demodectic mange should be included in the list of differential diagnoses in cases of periocular alterations of the skin of pigs.

Indexed as

AzetidinesSkinSpiro CompoundsAmbulatory Care FacilitiesAnimalsDiagnosis, DifferentialFemaleSwineAzetidinessarolanerSpiro CompoundsDemodex phylloidesIsoxazolinsSarolanerSkin hyperplasia

Identifiers

PMID38267960
PMCPMC10807167
OpenAlexW4391168773

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.