Evidence map›Paper›PMID 38267915›Full record

ArticleBMC ophthalmology2024

Retinitis after haematopoietic stem cell transplantation with multiple intraocular viral infections (cytomegalovirus, Epstein‒Barr virus and herpes simplex virus)- a case report.

Mengyun Liu, Hengqian He, Juntao Zhang, Shuanghua Xin, Qinkang Lu, Lifang Zhang, Weina Ren

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Mengyun Liu *Department of Ophthalmology, The Affiliated People's Hospital of Ningbo University, The Eye Hospital of Wenzhou Medical University (Ningbo Branch), 315040, Ningbo, People's Republic Of China.
Hengqian He *Department of Ophthalmology, The Affiliated People's Hospital of Ningbo University, The Eye Hospital of Wenzhou Medical University (Ningbo Branch), 315040, Ningbo, People's Republic Of China.
Juntao ZhangDepartment of Ophthalmology, The Affiliated People's Hospital of Ningbo University, The Eye Hospital of Wenzhou Medical University (Ningbo Branch), 315040, Ningbo, People's Republic Of China.
Shuanghua XinDepartment of Ophthalmology, The Affiliated People's Hospital of Ningbo University, The Eye Hospital of Wenzhou Medical University (Ningbo Branch), 315040, Ningbo, People's Republic Of China.
Qinkang LuDepartment of Ophthalmology, The Affiliated People's Hospital of Ningbo University, The Eye Hospital of Wenzhou Medical University (Ningbo Branch), 315040, Ningbo, People's Republic Of China.
Lifang ZhangDepartment of Ophthalmology, The Affiliated People's Hospital of Ningbo University, The Eye Hospital of Wenzhou Medical University (Ningbo Branch), 315040, Ningbo, People's Republic Of China.
Weina RenDepartment of Ophthalmology, The Affiliated People's Hospital of Ningbo University, The Eye Hospital of Wenzhou Medical University (Ningbo Branch), 315040, Ningbo, People's Republic Of China. rmrenweina@nbu.edu.cn.
Ningbo University · CN

Funding

Ningbo Clinical Research Center for Ophthalmology 2022L003Ningbo Clinical Research Center for Ophthalmology and the Project of NINGBO Leading Medical&Health Disipline 2016-S05Ningbo Natural Science Foundation 2023J170Ningbo Public Welfare Science and Technology Plan Project 2022S054Science and Technology Innovation 2025 Major Project of Ningbo 2021Z054Science and Technology Program of Traditional Chinese Medicine in Zhejiang Province 2024ZL920Zhejiang Medical and Health Science and Technology Plan Project 2023KY300Zhejiang Medical and Health Science and Technology Plan Project 2024KY372Zhejiang Provincial Natural Science Foundation of China LQ23H120001
6 · The paper itself

Abstract

backgroundTo report a case of retinitis with multiple intraocular viral infections after second haematopoietic stem cell transplantation. CASE PRESENTATION: A 39-year-old female patient developed retinitis after a second haematopoietic stem cell transplant. Right eye was tested for three viral infections- cytomegalovirus, Epstein‒Barr virus and herpes simplex virus, while left was infected with cytomegalovirus. The patient was subsequently treated with vitreous cavity ganciclovir injections, and 1 week later both eyes tested negative for aqueous humour viruses. DISCUSSION AND

conclusionCMV, EBV and HSV belong to the herpes virus family. They are all commonly observed in the body and represent opportunity infectious viruses. The retinitis they cause have different characteristics. But simultaneous infection of the eye by multiple viruses is quite rare. In this case, three viruses were detected in the patient's eye, but whether the retina was caused by all three viruses at the same time could not be determined. A satisfactory outcome was achieved after treatment with vitreous cavity ganciclovir injection.

Indexed as

Epstein-Barr Virus InfectionsHematopoietic Stem Cell TransplantationRetinitisVirus DiseasesAdultCytomegalovirusFemaleGanciclovirHerpesvirus 4, HumanHumansRetinaSimplexvirusGanciclovirCMVEBVHematopoietic stem cell transplantationHSVRetinitis

Identifiers

PMID38267915
PMCPMC10809542
OpenAlexW4391175597

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.