Evidence map›Paper›PMID 38267763›Full record

ArticleSkeletal radiology2024

Diffusion tensor imaging of hamstring muscles after acute strain injury and throughout recovery in collegiate athletes.

Christa M Wille, Samuel A Hurley, Elizabeth Schmida, Kenneth Lee, Richard Kijowski, Bryan C Heiderscheit

Abstract read
In one paragraph

Article in Skeletal radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Reliability and Repeatability of Diffusion Tensor Imaging in Healthy and Pathological Patellar Tendons.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2026
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Christa M WilleDepartment of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, USA.
Samuel A HurleyDepartment of Radiology, University of Wisconsin-Madison, Madison, WI, USA.
Elizabeth SchmidaDepartment of Orthopedics and Rehabilitation, University of Wisconsin-Madison, 6136 UW Medical Foundation Centennial Bldg, 1685 Highland Ave, Madison, WI, 53705, USA.
Kenneth LeeDepartment of Radiology, University of Wisconsin-Madison, Madison, WI, USA.
Richard KijowskiDepartment of Radiology, NYU Grossman School of Medicine, New York, NY, USA.
Bryan C HeiderscheitDepartment of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, USA. heiderscheit@ortho.wisc.edu.

Funding

NRSA Training CoreTL1TR002375 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI Vivek Prabhakaran · 2017 to 2026
$8.4M
NCATS NIH HHS TL1 TR002375
6 · The paper itself

Abstract

objectiveTo identify the region of interest (ROI) to represent injury and observe between-limb diffusion tensor imaging (DTI) microstructural differences in muscle following hamstring strain injury. MATERIALS AND

methodsParticipants who sustained a hamstring strain injury prospectively underwent 3T-MRI of bilateral thighs using T1, T2, and diffusion-weighted imaging at time of injury (TOI), return to sport (RTS), and 12 weeks after RTS (12wks). ROIs were using the hyperintense region on a T2-weighted sequence: edema, focused edema, and primary muscle injured excluding edema (no edema). Linear mixed-effects models were used to compare diffusion parameters between ROIs and timepoints and limbs and timepoints.

resultsTwenty-four participants (29 injuries) were included. A significant ROI-by-timepoint interaction was detected for all diffusivity measures. The edema and focused edema ROIs demonstrated increased diffusion at TOI compared to RTS for all diffusivity measures (p-values < 0.006), except λ

conclusionHyperintensity on T2-weighted imaging used to define the injured region holds promise in describing muscle microstructure following hamstring strain injury by demonstrating between-limb differences at TOI but not at follow-up timepoints.

Indexed as

Athletic InjuriesDiffusion Tensor ImagingHamstring MusclesSprains and StrainsAdolescentFemaleHumansMaleProspective StudiesReturn to SportYoung AdultAthletesDiffusion tensor imagingInjuriesMagnetic resonance imagingSkeletal muscle

Identifiers

PMID38267763
PMCPMC11905170

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.