Evidence map›Paper›PMID 38267601›Full record

ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2024

Clinical features and prognostic factors of patients with cancer-associated stroke.

Jun Sawada, Takayuki Katayama, Shiori Kikuchi-Takeguchi, Kohei Kano, Masato Saito, Nobuyuki Mitsui, Satoru Hiroshima, Manabu Kinoshita, Naoki Nakagawa

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Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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0cells of the map it votes in
4citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jun SawadaDivision of Cardiology, Nephrology, Pulmonology, and Neurology, Department of Internal Medicine, Asahikawa Medical University, Midorigaoka Higashi 2-1-1-1, Asahikawa, Hokkaido, 078-8510, Japan. sawajun@asahikawa-med.ac.jp.ORCID http://orcid.org/0000-0003-4078-9088
Takayuki KatayamaDepartment of Neurology, Asahikawa City Hospital, Asahikawa, Hokkaido, Japan.
Shiori Kikuchi-TakeguchiDivision of Cardiology, Nephrology, Pulmonology, and Neurology, Department of Internal Medicine, Asahikawa Medical University, Midorigaoka Higashi 2-1-1-1, Asahikawa, Hokkaido, 078-8510, Japan.
Kohei KanoDivision of Cardiology, Nephrology, Pulmonology, and Neurology, Department of Internal Medicine, Asahikawa Medical University, Midorigaoka Higashi 2-1-1-1, Asahikawa, Hokkaido, 078-8510, Japan.
Masato SaitoDepartment of Neurosurgery, Asahikawa Medical University, Asahikawa, Hokkaido, Japan.
Nobuyuki MitsuiDepartment of Neurosurgery, Asahikawa Medical University, Asahikawa, Hokkaido, Japan.
Satoru HiroshimaDepartment of Neurosurgery, Asahikawa Medical University, Asahikawa, Hokkaido, Japan.
Manabu KinoshitaDepartment of Neurosurgery, Asahikawa Medical University, Asahikawa, Hokkaido, Japan.
Naoki NakagawaDivision of Cardiology, Nephrology, Pulmonology, and Neurology, Department of Internal Medicine, Asahikawa Medical University, Midorigaoka Higashi 2-1-1-1, Asahikawa, Hokkaido, 078-8510, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCerebrovascular diseases in cancer patients significantly aggravate their condition and prognosis; therefore, prompt and accurate diagnosis and treatment are important. The purpose of this study was to investigate patient demographics, laboratory data, brain magnetic resonance imaging (MRI) findings, and prognosis among patients with stroke and cancer, especially cancer-associated ischemic stroke (CAIS).

methodsWe performed a retrospective, single-center study. We enrolled consecutive patients who had acute stroke and were admitted to our hospital between January 2011 and December 2021. We collected general demographic characteristics, cancer histopathological type, laboratory data, brain MRI findings, and prognosis data.

resultsAmong 2040 patients with acute stroke, a total of 160 patients (7.8%) had active cancer. The types of strokes were cerebral infarction, cerebral hemorrhage, subarachnoid hemorrhage, and transient ischemic attack in 124, 25, 5, and 6 patients, respectively. Among the patients with ischemic stroke, there were 69 cases of CAIS. Pancreas and adenocarcinoma were the most frequent types of primary tumor and histopathology. Patients with adenocarcinoma and those with cerebral infarctions in both bilateral anterior and posterior cerebral circulation areas showed higher D-dimer levels. Pancreatic cancer and high plasma D-dimer levels were associated with poor survival rate.

conclusionCAIS was seen more frequently in patients with pancreatic cancer and adenocarcinoma. Pancreatic cancer and high plasma D-dimer levels were potential factors of poor prognosis in patients with CAIS.

Indexed as

NeoplasmsAdenocarcinomaAdultAgedAged, 80 and overFemaleFibrin Fibrinogen Degradation ProductsHumansIschemic StrokeMagnetic Resonance ImagingMaleMiddle AgedPancreatic NeoplasmsPrognosisRetrospective StudiesStrokeFibrin Fibrinogen Degradation Productsfibrin fragment DAdenocarcinomaCancer-associated ischemic strokeD-dimerMagnetic resonance imageMultiple cerebral infarctionsPancreatic cancer

Identifiers

PMID38267601

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.