Evidence map›Paper›PMID 38267595›Full record

ReviewMetabolomics : Official journal of the Metabolomic Society2024

Challenges and perspectives for naming lipids in the context of lipidomics.

Michael Witting, Adnan Malik, Andrew Leach, Alan Bridge, Lucila Aimo, Matthew J Conroy, Valerie B O'Donnell, Nils Hoffmann, Dominik Kopczynski, Franck Giacomoni and 5 more

Abstract readReview
In one paragraph

Review in Metabolomics : Official journal of the Metabolomic Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Metabolite names and identifiers: how far are we from interoperability?Metabolomics : Official journal of the Metabolomic Society · 2026
    Article
  5. What's in a name? Metabolite identification: challenges and pitfalls in untargeted metabolomics.Metabolomics : Official journal of the Metabolomic Society · 2026
    Review
  6. Review
  7. Inflammation and resolution in obesity.Nature reviews. Endocrinology · 2025 · on this map
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Michael WittingMetabolomics and Proteomics Core, Helmholtz Zentrum München, Ingolstädter Landstraße 1, 85764, Neuherberg, Germany.
Adnan MalikEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
Andrew LeachEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
Alan BridgeSIB Swiss Institute of Bioinformatics, Centre Medical Universitaire, 1211, Geneva 4, Switzerland.
Lucila AimoSIB Swiss Institute of Bioinformatics, Centre Medical Universitaire, 1211, Geneva 4, Switzerland.
Matthew J ConroyDivision of Infection and Immunity, Systems Immunity Research Institute, School of Medicine, Cardiff University, Cardiff, CF14 4XN, UK.
Valerie B O'DonnellDivision of Infection and Immunity, Systems Immunity Research Institute, School of Medicine, Cardiff University, Cardiff, CF14 4XN, UK.
Nils HoffmannInstitute for Bio- and Geosciences (IBG-5), Forschungszentrum Jülich GmbH, 52425, Jülich, Germany.
Dominik KopczynskiInstitute for Analytical Chemistry, Universität Wien, Währingerstrasse 38, 1090, Vienna, Austria.
Franck GiacomoniUniversité Clermont Auvergne, INRAE, UNH, Plateforme d'Exploration du Métabolisme, MetaboHUB Clermont, Clermont-Ferrand, France.
Nils PaulheUniversité Clermont Auvergne, INRAE, UNH, Plateforme d'Exploration du Métabolisme, MetaboHUB Clermont, Clermont-Ferrand, France.
Amaury Cazenave GassiotSingapore Lipidomics Incubator, Life Sciences Institute, and Precision Medicine TRP, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Nathalie PoupinUMR1331 Toxalim, Université de Toulouse, INRAE, ENVT, INP-Purpan, UPS, Toulouse, France.
Fabien JourdanMetaboHUB, National Infrastructure of Metabolomics and Fluxomics ANR-11-INBS-0010, 31077, Toulouse, France.
Justine Bertrand-MichelMetaboHUB, National Infrastructure of Metabolomics and Fluxomics ANR-11-INBS-0010, 31077, Toulouse, France. Justine.bertrand-michel@inserm.fr.

Funding

COST EPILIPIDNET CA19105LipidMAPS LipidMAPS consortiumMetaboHUB MetaboHUB-ANR-11-INBS-0010
6 · The paper itself

Abstract

introductionLipids are key compounds in the study of metabolism and are increasingly studied in biology projects. It is a very broad family that encompasses many compounds, and the name of the same compound may vary depending on the community where they are studied.

objectivesIn addition, their structures are varied and complex, which complicates their analysis. Indeed, the structural resolution does not always allow a complete level of annotation so the actual compound analysed will vary from study to study and should be clearly stated. For all these reasons the identification and naming of lipids is complicated and very variable from one study to another, it needs to be harmonized. METHODS &

resultsIn this position paper we will present and discuss the different way to name lipids (with chemoinformatic and semantic identifiers) and their importance to share lipidomic results.

conclusionHomogenising this identification and adopting the same rules is essential to be able to share data within the community and to map data on functional networks.

Indexed as

LipidomicsMetabolomicsLipidsLipidsAnotationIdentificationInteroperabilityLipidomic

Identifiers

PMID38267595
PMCPMC10808356

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.