Evidence map›Paper›PMID 38267586›Full record

ArticleAnalytical and bioanalytical chemistry2024

Development of a molecularly imprinted polymer-based electrochemical sensor for the selective detection of nerve agent VX metabolite ethyl methylphosphonic acid in human plasma and urine samples.

Sermet Sezigen, S Irem Kaya, Nurgul K Bakirhan, Sibel A Ozkan

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In one paragraph

Article in Analytical and bioanalytical chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
6.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 3 countries.

Sermet SezigenDepartment of Medical CBRN Defense, University of Health Sciences, Ankara, Türkiye. sermet.sezigen@sbu.edu.tr.ORCID http://orcid.org/0000-0002-4658-5046
S Irem KayaDepartment of Analytical Chemistry, Gulhane Faculty of Pharmacy, University of Health Sciences, Ankara, Türkiye.
Nurgul K BakirhanDepartment of Analytical Chemistry, Gulhane Faculty of Pharmacy, University of Health Sciences, Ankara, Türkiye.
Sibel A OzkanDepartment of Analytical Chemistry, Faculty of Pharmacy, Ankara University, Ankara, Türkiye.
Ankara University · TRSağlık Bilimleri Üniversitesi · TR

Funding

CRDF Global 68878
6 · The paper itself

Abstract

This study focuses on the detection of ethyl methyl phosphonic acid (EMPA), a metabolite of the banned organophosphorus nerve agent VX. We developed an electrochemical sensor utilizing the molecularly imprinted polymer (MIP) based on 4-aminobenzoic acid (4-ABA) and tetraethyl orthosilicate for the selective detection of EMPA in human plasma and urine samples. The 4-ABA@EMPA/MIP/GCE sensor was constructed by a thermal polymerization process on a glassy carbon electrode and sensor characterization was performed by cyclic voltammetry and electrochemical impedance spectroscopy. The 4-ABA@EMPA/MIP/GCE sensor demonstrated impressive linear ranges 1.0 × 10

Indexed as

AnthracenesMolecular ImprintingNerve AgentsOrganophosphonatesOrganothiophosphorus CompoundsElectrochemical TechniquesElectrodesHumansLimit of DetectionMolecularly Imprinted PolymersOrganophosphorus CompoundsPolymers4-(2-anthryl)butanoic acidAnthracenesethyl methylphosphonic acidMolecularly Imprinted PolymersNerve AgentsOrganophosphonatesOrganophosphorus CompoundsOrganothiophosphorus CompoundsPolymersVX-agentElectrochemical sensorEthyl methyl phosphonic acidMolecularly imprinted polymersPlasmaUrineVX

Identifiers

PMID38267586
PMCPMC10861733
OpenAlexW4391188072

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.