Evidence map›Paper›PMID 38267582›Full record

ArticleNature2024

The HIV capsid mimics karyopherin engagement of FG-nucleoporins.

C F Dickson, S Hertel, A J Tuckwell, N Li, J Ruan, S C Al-Izzi, N Ariotti, E Sierecki, Y Gambin, R G Morris and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
19.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 84 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. HIV-1 capsid interactions with Nuclear Pore Complex components support nuclear entry via affinity gradient.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  7. Article
  8. Article
  9. MX2 Mediates Collapse of the HIV-1 Capsid.bioRxiv : the preprint server for biology · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Viral interference of nucleocytoplasmic transport.The Journal of biological chemistry · 2025
    Review
  19. Integrative mapping reveals molecular features underlying the mechanism of nucleocytoplasmic transport.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

C F Dickson *Department of Molecular Medicine, School of Biomedical Sciences, University of New South Wales, Sydney, New South Wales, Australia.ORCID 0000-0002-1972-4143
S Hertel *Department of Molecular Medicine, School of Biomedical Sciences, University of New South Wales, Sydney, New South Wales, Australia.ORCID 0009-0003-3428-3352
A J TuckwellDepartment of Molecular Medicine, School of Biomedical Sciences, University of New South Wales, Sydney, New South Wales, Australia.ORCID 0000-0002-8940-7768
N LiDepartment of Molecular Medicine, School of Biomedical Sciences, University of New South Wales, Sydney, New South Wales, Australia.
J RuanElectron Microscope Unit, Mark Wainwright Analytical Centre, University of New South Wales, Sydney, New South Wales, Australia.ORCID 0000-0001-8994-5235
S C Al-IzziEMBL Australia Node in Single Molecule Science, School of Biomedical Sciences, University of New South Wales, Sydney, New South Wales, Australia.
N AriottiInstitute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.
E SiereckiDepartment of Molecular Medicine, School of Biomedical Sciences, University of New South Wales, Sydney, New South Wales, Australia.ORCID 0000-0001-9970-868X
Y GambinDepartment of Molecular Medicine, School of Biomedical Sciences, University of New South Wales, Sydney, New South Wales, Australia.ORCID 0000-0001-7378-8976
R G MorrisEMBL Australia Node in Single Molecule Science, School of Biomedical Sciences, University of New South Wales, Sydney, New South Wales, Australia.
G J TowersInfection and Immunity, University College London, London, UK.ORCID 0000-0002-7707-0264
T BöckingDepartment of Molecular Medicine, School of Biomedical Sciences, University of New South Wales, Sydney, New South Wales, Australia.ORCID 0000-0003-1165-3122
D A JacquesDepartment of Molecular Medicine, School of Biomedical Sciences, University of New South Wales, Sydney, New South Wales, Australia. d.jacques@unsw.edu.au.ORCID 0000-0002-6426-4510
UNSW Sydney · AUThe University of Queensland · AUUniversity College London · GB

Funding

Medical Research Council MR/S023380/1Wellcome Trust
6 · The paper itself

Abstract

HIV can infect non-dividing cells because the viral capsid can overcome the selective barrier of the nuclear pore complex and deliver the genome directly into the nucleus

Indexed as

Capsid ProteinsGlycineHIVKaryopherinsMolecular MimicryNuclear PoreNuclear Pore Complex ProteinsPhenylalanineActive Transport, Cell NucleusCapsidDiffusionDipeptidesHumansIntrinsically Disordered ProteinsIn Vitro TechniquesPermeabilityCapsid ProteinsDipeptidesGlycineIntrinsically Disordered ProteinsKaryopherinsNuclear Pore Complex ProteinsPhenylalanine

Identifiers

PMID38267582
PMCPMC10881392
OpenAlexW4391160475

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.