Evidence map›Paper›PMID 38267581›Full record

ArticleNature2024

Transcription-replication interactions reveal bacterial genome regulation.

Andrew W Pountain, Peien Jiang, Tianyou Yao, Ehsan Homaee, Yichao Guan, Kevin J C McDonald, Magdalena Podkowik, Bo Shopsin, Victor J Torres, Ido Golding and 1 more

Abstract read
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Article
  2. Review
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  6. Article
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  9. Article
  10. Review
  11. Review
  12. Article
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  14. Article
  15. Article
  16. Article
  17. Article
  18. The type IV secretion system ofMicrobial genomics · 2025
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Andrew W PountainInstitute for Systems Genetics, NYU Grossman School of Medicine, New York, NY, USA.
Peien JiangInstitute for Systems Genetics, NYU Grossman School of Medicine, New York, NY, USA.
Tianyou YaoDepartment of Physics, University of Illinois at Urbana Champaign, Urbana, IL, USA.
Ehsan Homaee *Department of Physics, University of Illinois at Urbana Champaign, Urbana, IL, USA.
Yichao Guan *Department of Physics, University of Illinois at Urbana Champaign, Urbana, IL, USA.ORCID 0009-0005-7917-0022
Kevin J C McDonald *Department of Physics, University of Illinois at Urbana Champaign, Urbana, IL, USA.ORCID 0009-0007-5389-6452
Magdalena PodkowikDepartment of Medicine, Division of Infectious Diseases, NYU Grossman School of Medicine, New York, NY, USA.
Bo ShopsinDepartment of Medicine, Division of Infectious Diseases, NYU Grossman School of Medicine, New York, NY, USA.
Victor J TorresDepartment of Microbiology, NYU Grossman School of Medicine, New York, NY, USA.ORCID 0000-0002-7126-0489
Ido GoldingDepartment of Physics, University of Illinois at Urbana Champaign, Urbana, IL, USA.ORCID 0000-0002-4308-4959
Itai YanaiInstitute for Systems Genetics, NYU Grossman School of Medicine, New York, NY, USA. Itai.Yanai@nyulangone.org.ORCID 0000-0002-8438-2741

Funding

Spatiotemporal analysis of gene regulatory programs associated with GBS infection during pregnancyR01AI143290 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI RATNER, ADAM JONATHAN, YANAI, ITAI · 2019 to 2023
$3.8M
Mechanisms of MRSA intestinal colonizationR01AI140754 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SHOPSIN, BO · 2020 to 2024
$3.5M
Host-pathogen interactions during hospital adaptation of MRSAR01AI137336 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SHOPSIN, BO, YANAI, ITAI · 2019 to 2022
$3.3M
ILLUMINATING CELLULAR INDIVIDUALITY THROUGH BACTERIOPHAGE INFECTION (2nd Period)R35GM140709 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI Ido Golding · 2021 to 2026
$2.4M
Computational framework for analyzing and annotating single bacterium RNA-Seq dataR21AI169350 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI YANAI, ITAI · 2022 to 2023
$466k
NIAID NIH HHS R01 AI137336NIAID NIH HHS R01 AI140754NIAID NIH HHS R01 AI143290NIAID NIH HHS R21 AI169350NIGMS NIH HHS R35 GM140709
6 · The paper itself

Abstract

Organisms determine the transcription rates of thousands of genes through a few modes of regulation that recur across the genome

Indexed as

BacteriaDNA ReplicationGene Expression Regulation, BacterialGenome, BacterialTranscription, GeneticChromosomes, BacterialGene DosageGene Regulatory NetworksOperonSequence Analysis, RNA

Identifiers

PMID38267581
PMCPMC10923101

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.