Evidence map›Paper›PMID 38267524›Full record

ArticleNature neuroscience2024

Oligodendrocyte-axon metabolic coupling is mediated by extracellular K

Zoe J Looser, Zainab Faik, Luca Ravotto, Henri S Zanker, Ramona B Jung, Hauke B Werner, Torben Ruhwedel, Wiebke Möbius, Dwight E Bergles, L Felipe Barros and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Nature neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed
32.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 78 citations in OpenAlex.

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  9. When myelin breaks, tau aggregates - a new perspective on Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Review
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11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 3 countries.

Zoe J LooserInstitute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland.
Zainab FaikInstitute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland.
Luca RavottoInstitute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland.ORCID http://orcid.org/0000-0002-0431-9866
Henri S ZankerInstitute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland.
Ramona B JungDepartment of Neurogenetics, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.
Hauke B WernerDepartment of Neurogenetics, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.ORCID http://orcid.org/0000-0002-7710-5738
Torben RuhwedelDepartment of Neurogenetics, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.
Wiebke MöbiusDepartment of Neurogenetics, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.
Dwight E BerglesSolomon H. Snyder Department of Neuroscience, Johns Hopkins University, Baltimore, MD, USA.ORCID http://orcid.org/0000-0002-7133-7378
L Felipe BarrosCentro de Estudios Científicos (CECs), Valdivia, Chile.
Klaus-Armin NaveDepartment of Neurogenetics, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.ORCID http://orcid.org/0000-0001-8724-9666
Bruno WeberInstitute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland.ORCID http://orcid.org/0000-0002-9089-0689
Aiman S SaabInstitute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland. asaab@pharma.uzh.ch.ORCID http://orcid.org/0000-0003-3886-8369
University of Zurich · CHMax Planck Institute for Multidisciplinary SciencesJohns Hopkins University · USSan Sebastián University · CL

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Swiss National Science Foundation) Eccellenza 187000
6 · The paper itself

Abstract

The integrity of myelinated axons relies on homeostatic support from oligodendrocytes (OLs). To determine how OLs detect axonal spiking and how rapid axon-OL metabolic coupling is regulated in the white matter, we studied activity-dependent calcium (Ca

Indexed as

AxonsWhite MatterAnimalsHomeostasisLactatesMiceOligodendrogliaLactates

Identifiers

PMID38267524
PMCPMC10917689
OpenAlexW4391169202

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.