ArticleThe journal of nutrition, health & aging2024
Disparities in overall survival by varying duration of disability in activities of daily living in older people: A population-based cohort from Chinese Longitudinal Healthy Longevity Survey (CLHLS).
Article in The journal of nutrition, health & aging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 10 citations in OpenAlex.
- Article
- Associations of anti-inflammatory diet with cognitive impairment, physical dysfunction, depressive symptoms, and Multimorbidity in Chinese elderly: a national community-based study.BMC public health · 2025Article
- Associations of a body shape index, weight-adjusted waist index with the activities of daily living impairment in the middle-aged and elderly population: results from the China Health and Retirement Longitudinal Study.Frontiers in medicine · 2025Article
- Survival After Shunt Therapy in Normal-Pressure Hydrocephalus: A Meta-Analysis of 1614 Patients.Neurology international · 2024Review
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Authors and funding
11 authors at 3 institutions in 1 country.
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Abstract
objectivesTo investigate the association between duration of disability in activity of daily living (ADL) and overall survival in older individuals.
designA prospective cohort study.
settingCommunity-based data from Chinese Longitudinal Healthy Longevity Survey.
participantsIn total, 13,560 participants without ADL disability and 2772 participants with ADL disability at baseline were included. MEASUREMENTS: ADL disability was assessed using Katz index scale, which included six essential ADLs: dressing, bathing, transferring, toileting, continence, and eating. Dependence of each item was scored on a scale of 1, the maximum total score was 6. At baseline, duration of ADL disability was defined as the maximum duration among the six items. The study outcome was overall survival. Accelerated failure time models were constructed to investigate the association between duration of ADL disability and overall survival. Subgroup analyses by sex, age, and multimorbidites, as well as sensitive analyses were conducted.
resultsDuring 81,868.7 person-years follow-up, 11,092 deaths were recorded. Overall, ADL disability was associated with lower overall survival compared to non-ADL disability. With duration of ADL disability extending, the overall survival strikingly dropped in the first 12 months, reaching its lowest point with adjusted time ratio (TR) at 0.66 (95%CI: 0.61-0.72, p < 0.001), then moderately grew until the 60th month, finally stayed constant thereafter. Participants with ADL scores of 1-3 had higher survival compared to those with scores of 4-6, and both groups followed a similar trend of varied survival to the whole cohort. Moreover, subgroup analyses and sensitivity analyses showed the robustness of these findings.
conclusionsOur findings first address a golden time window for the older individuals with ADL disability. More attention should be given to them, especially in the first 12 months since diagnosis, to reduce mortality and extend the lifespan.
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