Evidence map›Paper›PMID 38266513›Full record

ArticleSchizophrenia research2024

The impact of early detection (ED) campaigns on care presentations: Beyond DUP reduction.

Hadar Hazan, Maria Ferrara, Sarah Riley, Fangyong Li, Bin Zhou, Emily Kline, Toni Gibbs-Dean, Sneha Karmani, Sümeyra N Tayfur, Cenk Tek and 2 more

Open access · greenAbstract read
In one paragraph

Article in Schizophrenia research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Hadar HazanYale Medical School, United States of America. Electronic address: hadarhazan@gmail.com.
Maria FerraraUniversity of Ferrara, Italy.
Sarah RileyYale Medical School, United States of America.
Fangyong LiYale Center for Analytical Sciences, United States of America.
Bin ZhouYale Center for Analytical Sciences, United States of America.
Emily KlineBoston University, United States of America.
Toni Gibbs-DeanYale Medical School, United States of America.
Sneha KarmaniYale Medical School, United States of America.
Sümeyra N TayfurYale Medical School, United States of America.
Cenk TekYale Medical School, United States of America.
Matcheri KeshavanHarvard Medical School, United States of America.
Vinod SrihariYale Medical School, United States of America.
Yale University · USBoston University · USHarvard University · USUniversity of Ferrara · IT

Funding

STEP-ED:Reducing Duration of Untreated Psychosis and its Impact in the U.S.R01MH103831 · NIMH · YALE UNIVERSITY · PI SRIHARI, VINOD H. · 2013 to 2017
$3.9M
NIMH NIH HHS R01 MH103831
6 · The paper itself

Abstract

We examined the effects of an early detection (ED) campaign (Mindmap), that successfully shortened the duration of untreated psychosis (DUP), on patient presentation profiles at two receiving coordinated specialty care (CSC) services. Data were collected between 2015 and 2019 during a test of ED delivered at one CSC (STEP, n = 147) compared to usual detection at another CSC (PREP, n = 63). Regression models were used to test the effects of ED and DUP on presentation. Before the launch of ED, there were no differences in presentation between STEP and PREP. However, the ED changed the profile of presentations to STEP such that patients were admitted with better negative and total symptoms scores, but worse GAF current and GAF social and with a greater decline in function over the prior year (GAF-Δ). Site-by-time interaction effects were not significant. During the campaign years, STEP vs. PREP recruited patients with better negative and total symptoms, GAF role, and pre-morbid adjustment scores but with worse positive symptoms, GAF current, and GAF-Δ. Nonetheless, mediation analysis revealed that DUP reduction accounted for very little (<8 %) of these differences in presentation. Early detection campaigns while successfully reducing access delays, can have salutary effects on presentation independent of DUP reduction.

Indexed as

Psychotic DisordersEarly DiagnosisHospitalizationHumansSchizophrenic PsychologyTime Factors

Identifiers

PMID38266513
PMCPMC10923115
OpenAlexW4391131804

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.