Evidence map›Paper›PMID 38266157›Full record

ArticleBlood advances2024

Longitudinal plasma proteomics in CAR T-cell therapy patients implicates neutrophils and NETosis in the genesis of CRS.

Christopher Flora, Mary Olesnavich, Yu Zuo, Erin Sandford, Rashmi Madhukar, Michelle Rozwadowski, Kavya Sugur, Andrew Ly, Ata Alpay Canbaz, Audra Shedeck and 10 more

Abstract read
In one paragraph

Article in Blood advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Coordinated expansion of CD163bioRxiv : the preprint server for biology · 2026
    Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Christopher FloraDepartment of Internal Medicine, Division of Hematology/Oncology, University of Michigan, Ann Arbor, MI.
Mary OlesnavichDepartment of Internal Medicine, Division of Hematology/Oncology, University of Michigan, Ann Arbor, MI.ORCID 0000-0002-4785-8130
Yu ZuoDepartment of Internal Medicine, Division of Rheumatology, University of Michigan, Ann Arbor, MI.
Erin SandfordDepartment of Internal Medicine, Division of Hematology/Oncology, University of Michigan, Ann Arbor, MI.ORCID 0000-0003-3498-8144
Rashmi MadhukarDepartment of Internal Medicine, Division of Hematology/Oncology, University of Michigan, Ann Arbor, MI.
Michelle RozwadowskiDepartment of Pediatrics, Division of Pediatric Hematology Oncology, University of Michigan, Ann Arbor, MI.ORCID 0000-0001-7864-383X
Kavya SugurDepartment of Internal Medicine, Division of Rheumatology, University of Michigan, Ann Arbor, MI.
Andrew LyJohns Hopkins University School of Medicine, Baltimore, MD.
Ata Alpay CanbazDivision of Hematological Malignancies and Bone Marrow Transplantation, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD.ORCID 0000-0001-8782-7518
Audra ShedeckDivision of Hematological Malignancies and Bone Marrow Transplantation, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD.
Gen LiDepartment of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, MI.
Marcus J GeerDepartment of Internal Medicine, Division of Hematology/Oncology, University of Michigan, Ann Arbor, MI.ORCID 0000-0001-9887-3464
Gregory A YanikDepartment of Pediatrics, Division of Pediatric Hematology Oncology, University of Michigan, Ann Arbor, MI.
Monalisa GhoshDepartment of Internal Medicine, Division of Hematology/Oncology, University of Michigan, Ann Arbor, MI.
David G FrameDepartment of Clinical Pharmacy, College of Pharmacy, University of Michigan, Ann Arbor, MI.
Challice L BonifantDivision of Hematological Malignancies and Bone Marrow Transplantation, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD.ORCID 0000-0001-9028-1683
Tania JainJohns Hopkins University School of Medicine, Baltimore, MD.ORCID 0000-0001-6854-773X
Jason S KnightDepartment of Internal Medicine, Division of Rheumatology, University of Michigan, Ann Arbor, MI.
Sung Won ChoiDepartment of Pediatrics, Division of Pediatric Hematology Oncology, University of Michigan, Ann Arbor, MI.ORCID 0000-0002-6321-3834
Muneesh TewariDepartment of Internal Medicine, Division of Hematology/Oncology, University of Michigan, Ann Arbor, MI.

Funding

Training Program in Molecular HematologyT32HL007622 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SUNG WON CHOI, Jordan A. Shavit · 1986 to 2026
$9.2M
Phase I/II clinical trial of HDAC inhibition for GVHD prevention in children, adolescents, and young adultsR01CA249211 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHOI, SUNG WON · 2020 to 2024
$2.2M
Roadmap 2.0: A randomized controlled trial using a technology-mediated platform in family caregivers of BMT patientsR01HL146354 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHOI, SUNG WON · 2019 to 2023
$1.8M
Patient-Oriented Research and Mentoring in Hematopoietic Cell TransplantationK24HL156896 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SUNG WON CHOI · 2021 to 2026
$870k
NCI NIH HHS R01 CA249211NHLBI NIH HHS K24 HL156896NHLBI NIH HHS R01 HL146354NHLBI NIH HHS T32 HL007622
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Immunotherapy, AdoptiveReceptors, Chimeric AntigenCytokinesHumansNeutrophilsProteomicsCytokinesReceptors, Chimeric Antigen

Identifiers

PMID38266157
PMCPMC10950819

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.