Evidence map›Paper›PMID 38266088›Full record

ArticleScience advances2024

Regulatory evolution tuning pigmentation intensity quantitatively in

Katharina Bachem, Xinyi Li, Stefano Ceolin, Bettina Mühling, David Hörl, Hartmann Harz, Heinrich Leonhardt, Laurent Arnoult, Sabrina Weber, Blair Matarlo and 2 more

Abstract read
In one paragraph

Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Evolution of repressive sequences within an enhancer contributed to morphological diversity in crucifer plants.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Article
  4. TheProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Katharina BachemDepartment of Evolutionary Ecology, Ludwig-Maximilians Universität München, München 82152, Germany.ORCID 0009-0005-4739-5825
Xinyi LiDepartment of Evolutionary Ecology, Ludwig-Maximilians Universität München, München 82152, Germany.ORCID 0009-0006-0121-6163
Stefano CeolinDepartment of Evolutionary Ecology, Ludwig-Maximilians Universität München, München 82152, Germany.
Bettina MühlingDepartment of Evolutionary Ecology, Ludwig-Maximilians Universität München, München 82152, Germany.ORCID 0000-0003-4901-0560
David HörlHuman Biology and Bioimaging, Ludwig-Maximilians Universität München, München 82152, Germany.ORCID 0000-0003-1710-1708
Hartmann HarzHuman Biology and Bioimaging, Ludwig-Maximilians Universität München, München 82152, Germany.ORCID 0000-0003-1218-2107
Heinrich LeonhardtHuman Biology and Bioimaging, Ludwig-Maximilians Universität München, München 82152, Germany.ORCID 0000-0002-5086-6449
Laurent ArnoultInstitut de Biologie du Développement de Marseille, Aix-Marseille Université, Marseille 13288, France.
Sabrina WeberDepartment of Evolutionary Ecology, Ludwig-Maximilians Universität München, München 82152, Germany.
Blair MatarloDepartment of Evolutionary Ecology, Ludwig-Maximilians Universität München, München 82152, Germany.ORCID 0009-0003-9191-5600
Benjamin Prud'hommeInstitut de Biologie du Développement de Marseille, Aix-Marseille Université, Marseille 13288, France.ORCID 0000-0003-2889-9081
Nicolas GompelDepartment of Evolutionary Ecology, Ludwig-Maximilians Universität München, München 82152, Germany.ORCID 0000-0003-3358-7963

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Quantitative variation in attributes such as color, texture, or stiffness dominates morphological diversification. It results from combinations of alleles at many Mendelian loci. Here, we identify an additional source of quantitative variation among species, continuous evolution in a gene regulatory region. Specifically, we examined the modulation of wing pigmentation in a group of fly species and showed that inter-species variation correlated with the quantitative expression of the pigmentation gene

Indexed as

DrosophilaPigmentationAllelesAnimalsPhenotypeSpecies Specificity

Identifiers

PMID38266088
PMCPMC10807792

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.