Evidence map›Paper›PMID 38265917›Full record

ArticleMolecular biology of the cell2024

Mechanical stretch regulates macropinocytosis in

Taylor D Skokan, Bert Hobmayer, Kara L McKinley, Ronald D Vale

Open access · greenAbstract read
In one paragraph

Article in Molecular biology of the cell, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
15.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Taylor D SkokanHoward Hughes Medical Institute and Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158.ORCID 0000-0002-2494-6672
Bert HobmayerDepartment of Zoology and Centre for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Technikerstr. 25, A-6020 Innsbruck, Austria.
Kara L McKinleyHoward Hughes Medical Institute and Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138.ORCID 0000-0001-6283-9168
Ronald D ValeHoward Hughes Medical Institute and Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158.ORCID 0000-0003-3460-2758
Howard Hughes Medical Institute · USUniversität Innsbruck · AT

Funding

Mechanisms modulating cell identity in regenerative mammalian epitheliaK99HD101021 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MCKINLEY, KARA LAVIDGE · 2019 to 2020
$194k
NICHD NIH HHS K99 HD101021
6 · The paper itself

Abstract

Cells rely on a diverse array of engulfment processes to sense, exploit, and adapt to their environments. Among these, macropinocytosis enables indiscriminate and rapid uptake of large volumes of fluid and membrane, rendering it a highly versatile engulfment strategy. Much of the molecular machinery required for macropinocytosis has been well established, yet how this process is regulated in the context of organs and organisms remains poorly understood. Here, we report the discovery of extensive macropinocytosis in the outer epithelium of the cnidarian

Indexed as

HydraAnimalsPinocytosis

Identifiers

PMID38265917
PMCPMC10916863
OpenAlexW4391167100

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.