Evidence map›Paper›PMID 38265914›Full record

ArticleIEEE transactions on medical imaging2024

Suppression of Subpixel Jitter in Resonant Scanning Systems With Phase-locked Sampling.

Vincent D Ching-Roa, Chi Z Huang, Michael G Giacomelli

Abstract read
In one paragraph

Article in IEEE transactions on medical imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Vincent D Ching-Roa
Chi Z Huang
Michael G Giacomelli

Funding

Two photon fluorescence microscopy for dermatologic surgery and biopsyR37CA258376 · NCI · UNIVERSITY OF ROCHESTER · PI Michael Gene Giacomelli · 2021 to 2026
$2.0M
Two photon microscopy and optical clearing for volumetric imaging of melanoma surgical marginsR21EB032839 · NIBIB · UNIVERSITY OF ROCHESTER · PI GIACOMELLI, MICHAEL GENE · 2022 to 2023
$364k
NCI NIH HHS R37 CA258376NIBIB NIH HHS R21 EB032839
6 · The paper itself

Abstract

Resonant scanning is critical to high speed and in vivo imaging in many applications of laser scanning microscopy. However, resonant scanning suffers from well-known image artifacts due to scanner jitter, limiting adoption of high-speed imaging technologies. Here, we introduce a real-time, inexpensive and all electrical method to suppress jitter more than an order of magnitude below the diffraction limit that can be applied to most existing microscope systems with no software changes. By phase-locking imaging to the resonant scanner period, we demonstrate an 86% reduction in pixel jitter, a 15% improvement in point spread function with resonant scanning and show that this approach enables two widely used models of resonant scanners to achieve comparable accuracy to galvanometer scanners running two orders of magnitude slower. Finally, we demonstrate the versatility of this method by retrofitting a commercial two photon microscope and show that this approach enables significant quantitative and qualitative improvements in biological imaging.

Indexed as

Image Processing, Computer-AssistedAlgorithmsAnimalsArtifactsEquipment DesignMicroscopy, ConfocalPhantoms, Imaging

Identifiers

PMID38265914
PMCPMC11147734

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.