Evidence map›Paper›PMID 38265368›Full record

ReviewMini reviews in medicinal chemistry2024

Bioactivities and Structure-Activity Relationships of Usnic Acid Derivatives: A Review.

Wen-Zhe Nie, Qing-Kun Shen, Zhe-Shan Quan, Hong-Yan Guo, Ya-Mei Li

Abstract readReview
PubMed Publisher
In one paragraph

Review in Mini reviews in medicinal chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wen-Zhe NieKey Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, 133002, China.
Qing-Kun ShenKey Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, 133002, China.
Zhe-Shan QuanKey Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, 133002, China.
Hong-Yan GuoKey Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Yanbian University, Yanji, 133002, China.
Ya-Mei LiDepartment of Pharmacy, Shandong Second Provincial General Hospital, Jinan, Shandong, China.

Funding

Education Department Project of Jilin JJKH20220559KJHigher Education Discipline Innovation Project D18012Jilin Scientific and Technological Development Program YDZJ202301ZYTS440Key Projects of Jilin Province Science and Technology Development Plan 20200404130YYNational Natural Science Foundation of China 81960626, 82060628
6 · The paper itself

Abstract

Usnic acid has a variety of biological activities, and has been widely studied in the fields of antibacterial, immune stimulation, antiviral, antifungal, anti-inflammatory and antiparasitic. Based on this, usnic acid is used as the lead compound for structural modification. In order to enhance the biological activity and solubility of usnic acid, scholars have carried out a large number of structural modifications, and found some usnic acid derivatives to be of more potential research value. In this paper, the structural modification, biological activity and structure-activity relationship of usnic acid were reviewed to provide reference for the development of usnic acid derivatives.

Indexed as

BenzofuransAnimalsAnti-Bacterial AgentsAntifungal AgentsAnti-Infective AgentsAnti-Inflammatory AgentsAntiparasitic AgentsAntiviral AgentsHumansMolecular StructureStructure-Activity RelationshipAnti-Bacterial AgentsAntifungal AgentsAnti-Infective AgentsAnti-Inflammatory AgentsAntiparasitic AgentsAntiviral AgentsBenzofuransusnic acidbiological activitynuclear translocation.phenolic compoundssignaling pathwaysstructural modificationsUsnic acid

Identifiers

PMID38265368

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.