ArticleMagnetic resonance in medicine2024
Universal dynamic fitting of magnetic resonance spectroscopy.
Article in Magnetic resonance in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Advanced methods in deuterium metabolic imaging.Magma (New York, N.Y.) · 2026Review
- Development and in vivo proof-of-concept of delayed alternating nutation tailored excitation point resolved spectroscopy (dante-press): a frequency-selective single voxel spectroscopy sequence applied to in vivo measurements of naa and glu at 7.0 T.Magma (New York, N.Y.) · 2026Article
- Age dependency of neurometabolite TMagnetic resonance in medicine · 2025Article
- Chemical shift and relaxation regularization improve the accuracy ofMagnetic resonance in medicine · 2025Article
- Metabolite TMagnetic resonance in medicine · 2025Article
- Simultaneous Concentration and TNMR in biomedicine · 2025Article
- Investigating Neurometabolite Changes in Response to Median Nerve Stimulation.Brain and behavior · 2025Article
- Functional magnetic resonance spectroscopy of prolonged motor activation using conventional and spectral GLM analyses.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Model-based frequency-and-phase correction ofMagnetic resonance in medicine · 2024Article
- Simultaneous multi-transient linear-combination modeling of MRS data improves uncertainty estimation.Magnetic resonance in medicine · 2024Article
- Metabolite TbioRxiv : the preprint server for biology · 2024Article
- Universal dynamic fitting of magnetic resonance spectroscopy.Magnetic resonance in medicine · 2024Article
- Model-based frequency-and-phase correction ofbioRxiv : the preprint server for biology · 2024Article
- Simultaneous multi-transient linear-combination modeling of MRS data improves uncertainty estimation.bioRxiv : the preprint server for biology · 2024Article
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Authors and funding
5 authors.
Funding
Abstract
purposeDynamic (2D) MRS is a collection of techniques where acquisitions of spectra are repeated under varying experimental or physiological conditions. Dynamic MRS comprises a rich set of contrasts, including diffusion-weighted, relaxation-weighted, functional, edited, or hyperpolarized spectroscopy, leading to quantitative insights into multiple physiological or microstructural processes. Conventional approaches to dynamic MRS analysis ignore the shared information between spectra, and instead proceed by independently fitting noisy individual spectra before modeling temporal changes in the parameters. Here, we propose a universal dynamic MRS toolbox which allows simultaneous fitting of dynamic spectra of arbitrary type.
methodsA simple user-interface allows information to be shared and precisely modeled across spectra to make inferences on both spectral and dynamic processes. We demonstrate and thoroughly evaluate our approach in three types of dynamic MRS techniques. Simulations of functional and edited MRS are used to demonstrate the advantages of dynamic fitting.
resultsAnalysis of synthetic functional
conclusionA toolbox for generalized and universal fitting of dynamic, interrelated MR spectra has been released and validated. The toolbox is shared as a fully open-source software with comprehensive documentation, example data, and tutorials.
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