Observational studyScandinavian journal of primary health care2024
Outcomes of antibiotic treatment for respiratory infections in children an observational study in primary care.
Observational study in Scandinavian journal of primary health care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02496559 (Children With Fever and Respiratory Symptoms at Out-of-hours Services in Norway), which is not on this map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Children With Fever and Respiratory Symptoms at Out-of-hours Services in Norway
Who cites it
1 citing paper in PubMed, 0 citations in OpenAlex.
- De-implementation of unnecessary antibiotic use for upper respiratory tract infections in ambulatory HIV care in Mozambique: a two-arm parallel cluster-randomized controlled hybrid type II trial.Implementation science communications · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAntibiotic resistance is an increasing global threat, accelerated by both misuse and overuse of antibiotics. Most antibiotics to humans are prescribed in primary care, commonly for respiratory symptoms, and there is a need for research on the usage of and outcomes after antibiotic treatment to counteract antibiotic resistance.
objectiveTo evaluate symptom duration, treatment length, and adverse events of antibiotic treatment in children. DESIGN AND
settingObservational study at four out-of-hours services and one paediatric emergency clinic in Norwegian emergency primary care. SUBJECTS: 266 children aged 0 to 6 years with fever or respiratory symptoms.
main outcome measuresDuration of symptoms and absenteeism from kindergarten/school, treatment length, and reported adverse events.
resultsThere were no differences in duration of symptoms, fever or absenteeism when comparing the groups prescribed (30.8%) and not prescribed (69.2%) antibiotics. This lack of difference remained when analysing the subgroup with otitis media.In the group prescribed antibiotics, 84.5% of parents reported giving antibiotics for 5-7 days, and 50.7% reported no difficulties. Adverse events of antibiotics were reported in 42.3% of the cases, the vast majority being gastrointestinal disturbances.
conclusionChildren with fever or respiratory symptoms experience similar duration of symptoms and absenteeism regardless of antibiotic treatment. A substantial number of parents reported adverse events when the child received antibiotics. Several parents experienced additional difficulties with the treatment, some ending treatment within day 4. TRIAL REGISTRATION NUMBER: NCT02496559; Results.
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