Evidence map›Paper›PMID 38264827›Full record

ReviewImmunotherapy2024

Established and emerging biomarkers of immunotherapy in renal cell carcinoma.

Yash Jani, Caroline S Jansen, Margo B Gerke, Mehmet Asim Bilen

Open access · greenAbstract readReview
In one paragraph

Review in Immunotherapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yash JaniMercer University, Macon, GA 31207, USA.ORCID 0000-0001-5872-523X
Caroline S JansenEmory University School of Medicine, Atlanta, GA 30322, USA.ORCID 0000-0001-9128-2004
Margo B GerkeEmory University School of Medicine, Atlanta, GA 30322, USA.ORCID 0009-0006-9002-7697
Mehmet Asim BilenWinship Cancer Institute of Emory University, Atlanta, GA 30322, USA.
Emory University · USMercer University · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM008169 · NIGMS · EMORY UNIVERSITY · PI GROSS, ROBERT E · 1987 to 2021
$20.3M
Examining the Mechanisms of Immune Cell Infiltration and Organization in a Murine Model of Renal Cancer and in Primary Human Renal TumorsF30CA243250 · NCI · EMORY UNIVERSITY · PI JANSEN, CAROLINE STEWART · 2020 to 2023
$214k
NCI NIH HHS F30 CA243250NIGMS NIH HHS T32 GM008169
6 · The paper itself

Abstract

Immunotherapies, such as immune checkpoint inhibitors, have heralded impressive progress for patient care in renal cell carcinoma (RCC). Despite this success, some patients' disease fails to respond, and other patients experience significant side effects. Thus, development of biomarkers is needed to ensure that patients can be selected to maximize benefit from immunotherapies. Improving clinicians' ability to predict which patients will respond to immunotherapy and which are most at risk of adverse events - namely through clinical biomarkers - is indispensable for patient safety and therapeutic efficacy. Accordingly, an evolving suite of therapeutic biomarkers continues to be investigated. This review discusses biomarkers for immunotherapy in RCC, highlighting current practices and emerging innovations, aiming to contribute to improved outcomes for patients with RCC.

Indexed as

Carcinoma, Renal CellKidney NeoplasmsBiomarkers, TumorHumansImmunotherapyBiomarkers, Tumorcancer immunologycheckpoint inhibitorsclinical immunologyimmunological markersimmunotherapy

Identifiers

PMID38264827
PMCPMC11913054
OpenAlexW4391173213

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.