Evidence map›Paper›PMID 38264713›Full record

ArticlePatterns (New York, N.Y.)2024

An adaptive federated learning framework for clinical risk prediction with electronic health records from multiple hospitals.

Weishen Pan, Zhenxing Xu, Suraj Rajendran, Fei Wang

Abstract read
In one paragraph

Article in Patterns (New York, N.Y.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Observational
  2. Federated Inverse Probability Treatment Weighting for Individual Treatment Effect Estimation.ACM transactions on intelligent systems and technology · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Federated systems for automated infection surveillance: a perspective.Antimicrobial resistance and infection control · 2024
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Weishen PanDepartment of Population Health Sciences, Weill Cornell Medical College, Cornell University, New York, NY 10065, USA.
Zhenxing XuDepartment of Population Health Sciences, Weill Cornell Medical College, Cornell University, New York, NY 10065, USA.
Suraj RajendranTri-Institutional Computational Biology & Medicine Program, Weill Cornell Medical College, Cornell University, New York, NY 10065, USA.
Fei WangDepartment of Population Health Sciences, Weill Cornell Medical College, Cornell University, New York, NY 10065, USA.

Funding

Computational Drug Repurposing for AD/ADRD with Integrative Analysis of Real World Data and Biomedical KnowledgeR01AG076234 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI Jiang Bian, Fei Wang · 2022 to 2026
$3.8M
Developing Suicide Risk Algorithms for Diverse Clinical Settings using Data FusionR01MH124740 · NIMH · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI ASELTINE, ROBERT H, CHEN, KUN · 2020 to 2023
$3.2M
Eligibility criteria design for Alzheimer's trials with real-world data and explainable AIR01AG080991 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI Jiang Bian, Fei Wang · 2023 to 2026
$3.1M
Disparities of Alzheimer's disease progression in Sexual Minority IndividualsR01AG080624 · NIA · UNIVERSITY OF FLORIDA · PI Jiang Bian, Yi Guo · 2023 to 2026
$3.1M
Tri-Institutional Training Program in Computational Biology & MedicineT32GM083937 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI CHRISTINI, DAVID J. · 2009 to 2018
$3.1M
Identification of Mild Cognitive Impairment using Machine Learning from Language and Behavior MarkersRF1AG072449 · NIA · MICHIGAN STATE UNIVERSITY · PI DODGE, HIROKO HAYAMA, WANG, FEI · 2021 to 2023
$2.6M
Post-Acute Sequelae of SARS-CoV-2 Infection and Subsequent Disease Progression in Individuals with AD/ADRD: Influence of the Social and Environmental Determinants of HealthRF1AG084178 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI BIAN, JIANG, HU, HUI · 2023 to 2023
$2.6M
NIA NIH HHS R01 AG076234NIA NIH HHS R01 AG080624NIA NIH HHS R01 AG080991NIA NIH HHS RF1 AG072449NIA NIH HHS RF1 AG084178NIGMS NIH HHS T32 GM083937NIMH NIH HHS R01 MH124740
6 · The paper itself

Abstract

Clinical risk prediction with electronic health records (EHR) using machine learning has attracted lots of attentions in recent years, where one of the key challenges is how to protect data privacy. Federated learning (FL) provides a promising framework for building predictive models by leveraging the data from multiple institutions without sharing them. However, data distribution drift across different institutions greatly impacts the performance of FL. In this paper, an adaptive FL framework was proposed to address this challenge. Our framework separated the input features into stable, domain-specific, and conditional-irrelevant parts according to their relationships to clinical outcomes. We evaluate this framework on the tasks of predicting the onset risk of sepsis and acute kidney injury (AKI) for patients in the intensive care unit (ICU) from multiple clinical institutions. The results showed that our framework can achieve better prediction performance compared with existing FL baselines and provide reasonable feature interpretations.

Indexed as

clinical risk prediciondistribution driftfederated learning

Identifiers

PMID38264713
PMCPMC10801228

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.