Evidence map›Paper›PMID 38264687›Full record

ArticleExploration (Beijing, China)2023

Early monitoring-to-warning Internet of Things system for emerging infectious diseases via networking of light-triggered point-of-care testing devices.

Yu Fu, Yan Liu, Wenlu Song, Delong Yang, Wenjie Wu, Jingyan Lin, Xiongtiao Yang, Jian Zeng, Lingzhi Rong, Jiaojiao Xia and 4 more

Abstract read
In one paragraph

Article in Exploration (Beijing, China), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yu FuMolecular Diagnosis and Treatment Center for Infectious Diseases Dermatology Hospital Southern Medical University Guangzhou China.
Yan LiuInstitute for Health Innovation and Technology National University of Singapore Singapore Singapore.
Wenlu SongMolecular Diagnosis and Treatment Center for Infectious Diseases Dermatology Hospital Southern Medical University Guangzhou China.
Delong YangDepartment of Burn Surgery the First People's Hospital of Foshan Foshan China.ORCID https://orcid.org/0000-0001-8913-3886
Wenjie WuDepartment of Burn and Plastic Surgery Guangzhou First People's Hospital South China University of Technology Guangzhou China.
Jingyan LinNational Clinical Research Center for Infectious Disease the Second Affiliated Hospital of Southern University of Science and Technology Shenzhen Third People's Hospital Shenzhen China.
Xiongtiao YangLonggang District Central Hospital of Shenzhen Shenzhen China.
Jian ZengLonggang District Central Hospital of Shenzhen Shenzhen China.
Lingzhi RongLonggang District Central Hospital of Shenzhen Shenzhen China.
Jiaojiao XiaLonggang District Central Hospital of Shenzhen Shenzhen China.
Hongyi LeiLonggang District Central Hospital of Shenzhen Shenzhen China.
Ronghua YangDepartment of Burn and Plastic Surgery Guangzhou First People's Hospital South China University of Technology Guangzhou China.
Mingxia ZhangNational Clinical Research Center for Infectious Disease the Second Affiliated Hospital of Southern University of Science and Technology Shenzhen Third People's Hospital Shenzhen China.
Yuhui LiaoMolecular Diagnosis and Treatment Center for Infectious Diseases Dermatology Hospital Southern Medical University Guangzhou China.ORCID https://orcid.org/0000-0003-4702-9516

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early monitoring and warning arrangements are effective ways to distinguish infectious agents and control the spread of epidemic diseases. Current testing technologies, which cannot achieve rapid detection in the field, have a risk of slowing down the response time to the disease. In addition, there is still no epidemic surveillance system, implementing prevention and control measures is slow and inefficient. Motivated by these clinical needs, a sample-to-answer genetic diagnosis platform based on light-controlled capillary modified with a photocleavable linker is first developed, which could perform nucleic acid separation and release by light irradiation in less than 30 seconds. Then, on site polymerase chain reaction was performed in a handheld closed-loop convective system. Test reports are available within 20 min. Because this method is portable, rapid, and easy to operate, it has great potential for point-of-care testing. Additionally, through multiple device networking, a real-time artificial intelligence monitoring system for pathogens was developed on a cloud server. Through data reception, analysis, and visualization, the system can send early warning signals for disease control and prevention. Thus, anti-epidemic measures can be implemented effectively, and deploying and running this system can improve the capabilities for the prevention and control of infectious diseases.

Indexed as

molecular diagnosticsmonitoring and warning systempathogen identificationpoint‐of‐care testingsample to answer

Identifiers

PMID38264687
PMCPMC10742204

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.