Evidence map›Paper›PMID 38264586›Full record

ArticleJournal of medical ultrasound

The Correlation between Carotid Artery Corrected Flow Time and Velocity Time Integral during Central Blood Volume Loss and Resuscitation.

Isabel Kerrebijn, Chelsea E Munding, Christine Horner, Sarah Atwi, Mai Elfarnawany, Andrew M Eibl, Joseph K Eibl, Jenna L Taylor, Chul Ho Kim, Bruce D Johnson and 1 more

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In one paragraph

Article in Journal of medical ultrasound. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Isabel KerrebijnFlosonics Medical, Toronto, ON, Canada.
Chelsea E MundingFlosonics Medical, Toronto, ON, Canada.
Christine HornerFlosonics Medical, Toronto, ON, Canada.
Sarah AtwiFlosonics Medical, Toronto, ON, Canada.
Mai ElfarnawanyFlosonics Medical, Toronto, ON, Canada.
Andrew M EiblFlosonics Medical, Toronto, ON, Canada.
Joseph K EiblFlosonics Medical, Toronto, ON, Canada.
Jenna L TaylorDepartment of Cardiovascular Diseases, Human Integrative and Environmental Physiology Laboratory, Mayo Clinic, Rochester, MN, USA.
Chul Ho KimDepartment of Cardiovascular Diseases, Human Integrative and Environmental Physiology Laboratory, Mayo Clinic, Rochester, MN, USA.
Bruce D JohnsonDepartment of Cardiovascular Diseases, Human Integrative and Environmental Physiology Laboratory, Mayo Clinic, Rochester, MN, USA.
Jon-Émile S KennyFlosonics Medical, Toronto, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Doppler ultrasound of the common carotid artery is used to infer central hemodynamics. For example, change in the common carotid artery corrected flow time (ccFT) and velocity time integral (VTI) are proposed surrogates of changing stroke volume. However, conflicting data exist which may be due to inadequate beat sample size and measurement variability - both intrinsic to handheld systems. In this brief communication, we determined the correlation between changing ccFT and carotid VTI during progressively severe central blood volume loss and resuscitation. Methods: Measurements were obtained through a novel, wireless, wearable Doppler ultrasound system. Sixteen participants (ages of 18-40 years with no previous medical history) were studied across 25 lower body-negative pressure protocols. Relationships were assessed using repeated-measures correlation regression models. Results: In total, 33,110 cardiac cycles comprise this analysis; repeated-measures correlation showed a strong, linear relationship between ccFT and VTI. The strength of the ccFT-VTI relationship was dependent on the number of consecutively averaged cardiac cycles (R Conclusions: These results positively support future clinical investigations employing common carotid artery Doppler as a surrogate for central hemodynamics.

Indexed as

Carotid arterycorrected flow timeDoppler ultrasoundfunctional hemodynamic monitoringvelocity time integralwearable technology

Identifiers

PMID38264586
PMCPMC10802870

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.