Evidence map›Paper›PMID 38264578›Full record

ArticleFrontiers in bioengineering and biotechnology2023

Mineral coated microparticles doped with fluoride and complexed with mRNA prolong transfection in fracture healing.

Anna Laura Nelson, Gianluca Fontana, Laura Chubb, Josh Choe, Katherine Williams, Dan Regan, Johnny Huard, William Murphy, Nicole Ehrhart, Chelsea Bahney

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Murine Progeria Model Exhibits Delayed Fracture Healing With Senescent Phenotype and Dysregulated Immune Response.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2026
    Article
  2. What's New in Musculoskeletal Basic Science.The Journal of bone and joint surgery. American volume · 2025
    Article
  3. Article
  4. Article
  5. Management of non-unions of the malleolar fractures- Current Evidence.Journal of clinical orthopaedics and trauma · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Anna Laura NelsonCenter for Regenerative and Personalized Medicine, Steadman Philippon Research Institute (SPRI), Vail, CO, United States.
Gianluca FontanaDepartment of Orthopedics and Rehabilitation, University of Wisconsin-Madison, Madison, WI, United States.
Laura ChubbDepartment of Clinical Sciences, Colorado State University, Fort Collins, CO, United States.
Josh ChoeDepartment of Orthopedics and Rehabilitation, University of Wisconsin-Madison, Madison, WI, United States.
Katherine WilliamsDepartment of Clinical Sciences, Colorado State University, Fort Collins, CO, United States.
Dan ReganDepartment of Microbiology, Colorado State University, Fort Collins, CO, United States.
Johnny HuardCenter for Regenerative and Personalized Medicine, Steadman Philippon Research Institute (SPRI), Vail, CO, United States.
William MurphyDepartment of Orthopedics and Rehabilitation, University of Wisconsin-Madison, Madison, WI, United States.
Nicole EhrhartDepartment of Clinical Sciences, Colorado State University, Fort Collins, CO, United States.
Chelsea BahneyCenter for Regenerative and Personalized Medicine, Steadman Philippon Research Institute (SPRI), Vail, CO, United States.

Funding

Integrated Training For Physician-ScientistsT32GM140935 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Anna Huttenlocher, Jeniel E Nett · 2021 to 2026
$6.5M
Therapeutic Application of Painless Nerve Growth Factor to Accelerate Endochondral Fracture RepairR01AR077761 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BAHNEY, CHELSEA SHIELDS · 2021 to 2025
$3.2M
Mineral Coated Microparticles for Stabilization and Delivery of Complexed mRNA for Healing of Long Bone DefectsF30AG077748 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI CHOE, JOSHUA ALAN · 2022 to 2024
$87k
NIAMS NIH HHS R01 AR077761NIA NIH HHS F30 AG077748NIGMS NIH HHS T32 GM140935
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

biomimeticbone regenerationfluoridemRNA deliverytransfection

Identifiers

PMID38264578
PMCPMC10803474

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.