Evidence map›Paper›PMID 38264358›Full record

ArticleEpilepsy & behavior reports2024

Neuromorphometric associations with mood, cognition, and self-reported exercise levels in epilepsy and healthy individuals.

Ayushe A Sharma, D Mackensie Terry, Johanna L Popp, Jerzy P Szaflarski, Roy C Martin, Rodolphe Nenert, Manmeet Kaur, Gabrielle A Brokamp, Mark Bolding, Jane B Allendorfer

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Epilepsy & behavior reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ayushe A SharmaUniversity of Alabama at Birmingham (UAB), Department of Neurology, Birmingham, AL, USA.
D Mackensie TerryUniversity of Alabama at Birmingham (UAB), Department of Neurology, Birmingham, AL, USA.
Johanna L PoppUniversity of Alabama at Birmingham (UAB), Department of Neurology, Birmingham, AL, USA.
Jerzy P SzaflarskiUniversity of Alabama at Birmingham (UAB), Department of Neurology, Birmingham, AL, USA.
Roy C MartinUniversity of Alabama at Birmingham (UAB), Department of Neurology, Birmingham, AL, USA.
Rodolphe NenertUniversity of Alabama at Birmingham (UAB), Department of Neurology, Birmingham, AL, USA.
Manmeet KaurUniversity of Alabama at Birmingham (UAB), Department of Neurology, Birmingham, AL, USA.
Gabrielle A BrokampUniversity of Alabama at Birmingham (UAB), Department of Neurology, Birmingham, AL, USA.
Mark BoldingUniversity of Alabama at Birmingham (UAB), Department of Radiology, Birmingham, AL, USA.
Jane B AllendorferUniversity of Alabama at Birmingham (UAB), Department of Neurology, Birmingham, AL, USA.

Funding

UAB Research Training Program in Neurobiology of Cognition and Cognitive DisordersT32NS061788 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Farah Dominique Lubin · 2008 to 2026
$4.5M
Brain temperature and tissue microstructure in treatment-resistant epilepsyF31NS129288 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SHARMA, AYUSHE ALICIA · 2022 to 2023
$58k
NINDS NIH HHS F31 NS129288NINDS NIH HHS T32 NS061788
6 · The paper itself

Abstract

Regular physical activity may promote beneficial neuroplasticity, e.g., increased hippocampus volume. However, it is unclear whether self-reported physical exercise in leisure (PEL) levels are associated with the brain structure features demonstrated by exercise interventions. This pilot study investigated the relationship between PEL, mood, cognition, and neuromorphometry in patients with idiopathic generalized epilepsy (IGEs) compared to healthy controls (HCs). Seventeen IGEs and 19 age- and sex-matched HCs underwent magnetic resonance imaging (MRI) at 3T. The Baecke Questionnaire of Habitual Physical Activity, Profile of Mood States, and Montreal Cognitive Assessment (MoCA) assessed PEL, mood, and cognition, respectively. Structural MRI data were analyzed by voxel- and surface-based morphometry. IGEs had significantly lower PEL (

Indexed as

CognitionExercise levelsGrey matter volumeHippocampusIdiopathic generalized epilepsyMood

Identifiers

PMID38264358
PMCPMC10803905

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.