Evidence map›Paper›PMID 38264088›Full record

ArticleFrontiers in neurology2023

Comparative analysis of albumin quotient and total CSF protein in immune-mediated neuropathies: a multicenter study on diagnostic implications.

Tabea Seeliger, Stefan Gingele, Yunus Emre Güzeloglu, Lena Heitmann, Benjamin Lüling, Felix Kohle, Hannah Preßler, Frauke Stascheit, Jeremias Motte, Anna Lena Fisse and 3 more

Abstract read
In one paragraph

Article in Frontiers in neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Observational
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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Tabea SeeligerDepartment of Neurology, Hannover Medical School, Hannover, Germany.
Stefan GingeleDepartment of Neurology, Hannover Medical School, Hannover, Germany.
Yunus Emre GüzelogluDepartment of Neurology, Hannover Medical School, Hannover, Germany.
Lena HeitmannDepartment of Neurology, Hannover Medical School, Hannover, Germany.
Benjamin LülingDepartment of Neurology, St Josef Hospital, Ruhr University Bochum, Bochum, Germany.
Felix KohleDepartment of Neurology, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany.
Hannah PreßlerDepartment of Neurology with Experimental Neurology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität, Berlin, Germany.
Frauke StascheitDepartment of Neurology with Experimental Neurology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität, Berlin, Germany.
Jeremias MotteDepartment of Neurology, St Josef Hospital, Ruhr University Bochum, Bochum, Germany.
Anna Lena FisseDepartment of Neurology, St Josef Hospital, Ruhr University Bochum, Bochum, Germany.
Thomas GrüterDepartment of Neurology, St Josef Hospital, Ruhr University Bochum, Bochum, Germany.
Kalliopi PitarokoiliDepartment of Neurology, St Josef Hospital, Ruhr University Bochum, Bochum, Germany.
Thomas SkripuletzDepartment of Neurology, Hannover Medical School, Hannover, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Blood-cerebrospinal fluid (CSF) barrier dysfunction is pivotal for diagnosing immune-mediated neuropathies, especially in spinal nerve root inflammation. Typically, either total CSF protein or the CSF to serum albumin ratio (Q Methods: In our multicenter research, we collected retrospective CSF data from patients suffering from immune-mediated neuropathies across four German research centers. These parameters were analyzed in relation to their clinical characteristics. Results: Out of 419 samples, 36 (8.6%) displayed a notable variation between total CSF protein and Q Discussion: Our work confirms the crucial role of Q

Indexed as

barrier-dysfunctionblood-cerebrospinal fluid-barrierCSFimmune-mediated neuropathiesQAlb

Identifiers

PMID38264088
PMCPMC10803547

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.