Evidence map›Paper›PMID 38263986›Full record

ArticleObesity science & practice2024

Weight regain after total meal replacement very low-calorie diet program with and with-out anti-obesity medications.

Lizeth Cifuentes, Francesca Galbiati, Hussain Mahmud, David Rometo

Abstract read
In one paragraph

Article in Obesity science & practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Obesity and its management in primary care setting.Journal of diabetes and its complications · 2025
    Review
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lizeth CifuentesDepartment of Medicine Division of General Internal Medicine University of Pittsburgh Medical Center Pittsburgh Pennsylvania USA.ORCID https://orcid.org/0000-0001-7865-2947
Francesca GalbiatiDepartment of Medicine Division of Endocrinology, Diabetes, and Hypertension Brigham and Women's Hospital Harvard Medical School Boston Massachusetts USA.ORCID https://orcid.org/0000-0003-0744-2541
Hussain MahmudDepartment of Medicine Division of Endocrinology, Diabetes, and Metabolism University of Pittsburgh Medical Center Pittsburgh Pennsylvania USA.
David RometoDepartment of Medicine Division of Endocrinology, Diabetes, and Metabolism University of Pittsburgh Medical Center Pittsburgh Pennsylvania USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Very low-calorie diets (VLCDs) employing total meal replacement (TMR) offer substantial short-term weight loss. Concurrently, anti-obesity medications (AOMs) have shown promise as adjunctive treatments when combined with VLCDs. Aims: This study aimed to investigate the impact of adjuvant AOMs on weight loss and weight regain within a comprehensive lifestyle program. Methods: This is a retrospective study of patients with obesity enrolled in VLCD/TMR programs,  specifically the OPTIFAST program. Results: Data from 206 patients (68% women, mean age 52.39 ± 13.05 years, BMI 41.71 ± 7.04 kg/m Conclusion: The findings highlighted the potential of AOMs and VLCD/TMR as effective strategies for long-term weight management in individuals with obesity.

Indexed as

obesitypharmacotherapytotal meal replacement

Identifiers

PMID38263986
PMCPMC10804351

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.