ReviewJournal of intensive medicine2024
Severe dengue in the intensive care unit.
Review in Journal of intensive medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Burden of Dengue in Pregnant Individuals: A Systematic Literature Review.The American journal of tropical medicine and hygiene · 2026Pooled it
- Risk of cognitive decline among patients with dengue virus infection: a systematic review.The international journal of neuropsychopharmacology · 2024Pooled it
- First laboratory-confirmed fatal dengue virus infection and its implications for national arboviral surveillance in Liberia.IJID regions · 2026Article
- Dengue and aging: challenges and opportunities in prevention and care. A narrative review.Emerging microbes & infections · 2026Review
- The Unusual Coexistence of Chronic Lymphocytic Leukemia, Dengue Fever, and Acute Kidney Injury: A Case Report.Clinical case reports · 2026Article
- Clinical and haematological correlates of severe dengue using 2023 epidemic data: A multicentre tertiary hospital-based analysis from Dhaka, Bangladesh.PLoS neglected tropical diseases · 2026Article
- Article
- Metabolic and cardiovascular comorbidities as predictors of severe dengue in Vietnamese adults: a retrospective study, 2022-2024.Osong public health and research perspectives · 2026Article
- Improved and customized dengue serodiagnostics through combined NS1/IgM testing and novel dual-cut-off IgG ELISA.PLoS neglected tropical diseases · 2026Article
- Health-related quality of life and associated factors among hospitalized dengue patients in Bangladesh: a cross-sectional study.BMC infectious diseases · 2026Observational
- Utility of the neutrophil-to-lymphocyte ratio in predicting plasma leakage amongst adults with dengue fever.Internal and emergency medicine · 2026Article
- Evaluating the economic burden of dengue in Sri Lanka: A systematic review of costs from 2010 to 2024.IJID regions · 2026Review
- Article
- Detection of novelFrontiers in microbiology · 2026Article
- Article
- Validation of China's 2025 high-risk criteria in RT-PCR-confirmed chikungunya inpatients: a single-centre retrospective cohort.BMC infectious diseases · 2025Article
- Article
- Severe dengue in adults admitted to intensive care units on réunion island: clinical spectrum, outcomes, and predictors of mortality.Critical care (London, England) · 2025Article
- Mechanistic Insights into Hepatic Pathogenesis of Dengue Virus Serotype-2: Host-Virus Interactions, Immune Dysregulation, and Therapeutic Perspectives.International journal of molecular sciences · 2025Review
- Integrating machine learning and time-to-event models to explain and predict risk of hospitalization due to dengue in Colombia.Scientific reports · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dengue fever is considered the most prolific vector-borne disease in the world, with its transmission rate increasing more than eight times in the last two decades. While most cases present mild to moderate symptoms, 5% of patients can develop severe disease. Although the mechanisms are yet not fully comprehended, immune-mediated activation leading to excessive cytokine expression is suggested as a cause of the two main findings in critical patients: increased vascular permeability that may shock and thrombocytopenia, and coagulopathy that can induce hemorrhage. The risk factors of severe disease include previous infection by a different serotype, specific genotypes associated with more efficient replication, certain genetic polymorphisms, and comorbidities such as diabetes, obesity, and cardiovascular disease. The World Health Organization recommends careful monitoring and prompt hospitalization of patients with warning signs or propensity for severe disease to reduce mortality. This review aims to update the diagnosis and management of patients with severe dengue in the intensive care unit.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.